Related Experiment Video

Updated: Jul 29, 2026

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid
09:58

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

Published on: January 31, 2012

Anabolic and catabolic responses of human articular cells to growth factors

C W Castor, C G Ragsdale, A R Cabral

    The Journal of Rheumatology
    |May 1, 1987
    PubMed

    Keywords:
    Human joint cell metabolismGrowth factor effectsSynovial cell activityCartilage repair mechanisms

    More Related Videos

    3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation12:37

    3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation

    Published on: October 7, 2015

    An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants07:10

    An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants

    Published on: November 3, 2019

    Related Concept Videos

    Growth of Cartilage and Bone Tissue01:27

    Growth of Cartilage and Bone Tissue

    Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
    TGF - β Signaling Pathway01:16

    TGF - β Signaling Pathway

    The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors are of three kinds RI, RII, and RIII. The RI...
    Glycosaminoglycans01:23

    Glycosaminoglycans

    Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
    GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
    Hyaluronic...
    Cell-matrix's Response to Mechanical Forces01:13

    Cell-matrix's Response to Mechanical Forces

    In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
    Anchoring junctions mechanically attach a cell to the...