Safety assessment in the research and development of new chemicals

A variety of testings to be incorporated in the research and development program of new chemicals to assess their fates and effects onto man and his environment should be so designed as to duly furnish reliable preliminary information. A rapid in vivo assay for animal carcinogenicity and a model ecosystem for bioaccumulation in aquatic organisms are discussed as examples of these brief testings, while further research needs are mentioned to ultimately assess the impacts of chemicals to the whole environment.