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Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
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Transmission Electron Microscopy01:15

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In 1931, physicist Ernst Ruska—building on the idea that magnetic fields can direct an electron beam just as lenses can direct a beam of light in an optical microscope—developed the first prototype of the electron microscope. This development led to the development of the field of electron microscopy. In the transmission electron microscope (TEM), electrons are produced by a hot tungsten element and accelerated by a potential difference in an electron gun, which gives them up to 400...
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Total Internal Reflection Fluorescence Microscopy01:05

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
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Related Experiment Video

Updated: Aug 25, 2025

Direct Imaging of Laser-driven Ultrafast Molecular Rotation
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Quantum gas microscope assisted with T-shape vacuum viewports.

Ye Tian, Zhongchi Zhang, Jilai Ye

    Optics Express
    |October 19, 2022
    PubMed
    Summary

    We developed an integrated quantum gas microscope with external optics for high-resolution imaging of cold atoms. This microscope achieves a high numerical aperture and minimizes distortions for improved atomic distribution analysis.

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    Area of Science:

    • Quantum optics
    • Atomic physics
    • Microscopy

    Background:

    • Quantum gas microscopy is crucial for imaging cold atom distributions in experiments.
    • Existing microscopes face challenges with optical access and distortion.

    Purpose of the Study:

    • To design and build an integrated quantum gas microscope with external optical components.
    • To achieve high numerical aperture and long working distance for improved imaging.
    • To mitigate optical distortions caused by vacuum viewports.

    Main Methods:

    • Designed and constructed an external optical system for quantum gas microscopy.
    • Utilized a T-shape vacuum viewport to minimize flatness distortion.
    • Employed scanning near-field microscopy (SNOM) for calibration.

    Main Results:

    • Achieved a large numerical aperture (NA) of 0.75.
    • Maintained a long working distance (13 mm total) for side optical access.
    • Minimized viewport-induced distortions, reaching a Strehl ratio of 0.9204.

    Conclusions:

    • The integrated quantum gas microscope offers high-resolution imaging capabilities.
    • The design effectively addresses challenges of optical access and distortion in cold-atom experiments.
    • This advanced microscopy technique enhances the study of quantum gases.