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Transient Sideroblastic Anemia Post-COVID-19 Infection
Nikhil Mukhi1, Luis R Soto2, Aparna Vuppala3
1Hematology/Oncology, St. Francis Hospital, Tulsa, USA.
Cureus
|October 19, 2022
Summary
A patient developed severe anemia with ring sideroblasts post-COVID-19. This condition, possibly a delayed COVID-19 manifestation, eventually improved spontaneously.
Area of Science:
- Hematology
- Infectious Diseases
- Oncology
Background:
- COVID-19 is known to cause various hematological complications.
- Anemia, particularly with reticulocytopenia, can occur post-viral infections.
Observation:
- A 57-year-old male presented with fatigue and dyspnea three months after COVID-19 recovery.
- He exhibited severe anemia with reticulocytopenia, leading to a diagnosis of sideroblastic anemia.
Findings:
- Bone marrow examination revealed erythroid-predominant hematopoiesis with 79% ring sideroblasts and no dysplasia.
- Despite initial treatment with erythropoiesis-stimulating agents and luspatercept, anemia improved spontaneously after 12 months, with repeat biopsy showing 39% ring sideroblasts.
Implications:
- This case suggests a potential delayed hematological manifestation of COVID-19, specifically sideroblastic anemia.
- Further research is needed to understand the link between COVID-19 and sideroblastic anemia.
- The spontaneous resolution warrants investigation into the long-term effects of COVID-19 on bone marrow function.
Keywords:
covid-19myelodysplastic diseasemyeloproliferative neoplasm diseasepost-covid-19 conditionsreticulocytopeniasideroblastic anemiaMore Related Videos
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