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A community-science approach identifies genetic variants associated with three color morphs in ball pythons (Python
Autumn R Brown1, Kaylee Comai1, Dominic Mannino1
1Department of Biology, Eastern Michigan University, Ypsilanti, MI, United States of America.
Plos One
|October 19, 2022
Summary
Researchers investigated the genetics behind three ball python (Python regius) color morphs by analyzing shed skins. Genetic variants in TYR, OCA2, and TYRP1 genes were identified, explaining the melanin deficiency in Albino, Lavender Albino, and Ultramel morphs.
Area of Science:
- Genetics
- Herpetology
- Molecular Biology
Background:
- Ball pythons (Python regius) exhibit diverse color morphs, offering insights into reptile coloration genetics.
- Melanin production is crucial for coloration, and its disruption leads to distinct phenotypes.
Purpose of the Study:
- To investigate the genetic basis of three ball python color morphs: Albino, Lavender Albino, and Ultramel.
- To identify specific genetic variants responsible for melanin deficiency in these morphs.
Main Methods:
- A community-science approach was employed, collecting shed skins from pet ball pythons.
- DNA was extracted from shed skins to identify genetic variants.
- Homologs of genes involved in melanin production in other vertebrates were analyzed.
Main Results:
- The Albino morph is linked to variants in the TYR gene.
- The Lavender Albino morph is associated with a deletion in the OCA2 gene.
- The Ultramel morph shows variants in the TYRP1 gene.
Conclusions:
- This study identifies genetic variants underlying specific ball python color morphs.
- Community-sourced samples are valuable for genetic research in pet species.
- The findings contribute to understanding reptile coloration genetics.
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