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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

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Left Ventricular Function and Geometry of Children with Chronic Kidney Disease (CKD) in a Resource-Poor Setting of

D K Adiele1, H U Okafor2, N C Ojinnaka3

  • 1Paediatric Cardiology Unit, Department of Paediatrics, College of Medicine, University of Nigeria/University of Nigeria Teaching Hospital (UNTH), Ituku- Ozalla, Enugu State, Nigeria.

West African Journal of Medicine
|October 19, 2022
PubMed

Insights

Children with Chronic Kidney Disease (CKD) show high rates of left ventricular abnormalities. Early detection and intervention are crucial for managing cardiovascular risks in pediatric CKD patients.

Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Health in Children
  • Renal Function Impairment

Background:

  • Chronic Kidney Disease (CKD) is a progressive condition leading to end-stage renal disease.
  • Cardiovascular complications significantly contribute to morbidity and mortality in CKD patients.

Purpose of the Study:

  • To compare the prevalence of left ventricular (LV) function and geometry changes in children with CKD versus healthy controls.
  • To identify specific echocardiographic alterations in pediatric CKD.

Main Methods:

  • A descriptive cross-sectional study involving children aged 6-17 with CKD and matched healthy controls.
  • Echocardiography was used to assess LV function and geometry.
  • Data analysis included statistical comparisons of prevalence and characteristics.

Main Results:

  • The study identified a high incidence of LV abnormalities in pediatric CKD patients.
  • Prevalence included Left Ventricular Hypertrophy (LVH) in 50.0%, eccentric LVH in 33.3%, and Left Ventricular Dilatation (LVD) in 41.7%.
  • Diastolic dysfunction was observed in 37.5% and systolic dysfunction in 8.3% of CKD subjects.

Conclusions:

  • Abnormalities in left ventricular geometry and function are highly prevalent in children with CKD.
  • Urgent intervention strategies are recommended to address these cardiovascular changes in pediatric CKD.
Abstract

Keywords:
ChildrenChronic kidney diseaseLeft ventricular functionLeft ventricular geometry

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