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Updated: Aug 24, 2025

Immunophenotyping of Orthotopic Homograft Syngeneic of Murine Primary KPC Pancreatic Ductal Adenocarcinoma by Flow Cytometry
Published on: October 9, 2018
Two types of biomarker-dependent chemo-immunotherapy for pancreatic cancer?
1Leiden University Medical Center, Leiden, The Netherlands; ISA Pharmaceuticals, Leiden, The Netherlands.
Abstract:
Padron et al.1 studied the combination of chemotherapy (gemcitabine and nab-paclitaxel) with either an anti-PD1 (nivolumab) or an anti-CD40 (sotigalimab) antibody in metastatic pancreatic cancer. They showed clinical benefit in individuals with unique biomarkers for each treatment combination.
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