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Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Related Experiment Video

Updated: Aug 24, 2025

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
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Large Bore Portal Vein Thrombectomy: An Inari FlowTriever Case Series.

Ian W Sullivan1, Adam Fonseca2, McKenzie Brown3

  • 1Loyola University Medical Center Department of Interventional Radiology, 2160 S 1st Avenue, Maywood, IL, 60153, USA. isullivan@tuftsmedicalcenter.org.

Cardiovascular and Interventional Radiology
|October 19, 2022
PubMed
Summary

Large bore mechanical thrombectomy effectively treats portal vein thrombus (PVT) in cirrhosis patients, often resolving it in one session. This procedure, combined with transjugular intrahepatic portosystemic shunt (TIPS) placement, offers a feasible solution for portal hypertension complications.

Keywords:
Portal veinThrombectomyThrombosisTransjugular intrahepatic portosystemic shunt (TIPS)

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Area of Science:

  • Hepatology
  • Interventional Radiology
  • Vascular Surgery

Background:

  • Portal vein thrombus (PVT) complicates cirrhosis, worsening portal hypertension and liver function.
  • PVT negatively impacts outcomes for liver transplant candidates.
  • Effective PVT treatment is crucial for managing cirrhotic patients.

Purpose of the Study:

  • To describe the use of large bore mechanical thrombectomy for PVT in cirrhotic patients.
  • To evaluate the Inari FlowTriever device for PVT treatment.
  • To assess outcomes of thrombectomy performed during or after transjugular intrahepatic portosystemic shunt (TIPS) placement.

Main Methods:

  • Retrospective case series of ten patients with cirrhosis and PVT.
  • Large bore mechanical thrombectomy using the Inari FlowTriever device.
  • Thrombectomy performed concurrently with TIPS or after shunt thrombosis.

Main Results:

  • Technical success in all thrombectomy procedures.
  • Complete PVT resolution in a majority of patients during a single session.
  • Sustained complete PVT resolution without recurrence during a mean follow-up of 13.3 months.

Conclusions:

  • Large bore mechanical thrombectomy combined with TIPS is a feasible and effective treatment for acute/subacute PVT.
  • The procedure often leads to complete PVT resolution in a single session.
  • This approach improves outcomes for cirrhotic patients with portal hypertension and PVT.