Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acoustic Streaming-Based 3D Cell Focusing and Plasma Separation.

Micromachines·2026
Same author

DNA methylation biomarkers associated with early gastric cardia carcinogenesis.

Clinical and experimental medicine·2026
Same author

Curcumol alleviates acute pancreatitis by inhibiting RIPK1/RIPK3/MLKL pathway-mediated necroptosis: integrated bioinformatics, network pharmacology, molecular docking and dynamics simulations, and experimental validation.

International immunopharmacology·2026
Same author

Machine Learning-Enhanced Microfluidic Impedance Platform for Rare Cell Analysis.

Analytical chemistry·2026
Same author

Dynamic Color Filtering Based on Fabry-Pérot Cavities Incorporating Vanadium Dioxide.

ACS applied materials & interfaces·2026
Same author

Flexible, stretchable, on-chip optical tweezers for high-throughput bioparticle manipulation.

Light, science & applications·2026

Related Experiment Video

Updated: Aug 24, 2025

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.2K

Tunable and Dynamic Optofluidic Microlens Arrays Based on Droplets.

Li Liang1, Xuejia Hu2, Yang Shi3

  • 1School of Physics and Electronic Technology, Anhui Normal University, Wuhu241000, China.

Analytical Chemistry
|October 20, 2022
PubMed
Summary

This study presents a novel optofluidic method for creating tunable liquid microlens arrays (MLAs). These adaptable liquid MLAs offer adjustable focusing for advanced micro-optical systems and imaging applications.

More Related Videos

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.4K
Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.3K

Related Experiment Videos

Last Updated: Aug 24, 2025

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.2K
A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.4K
Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.3K

Area of Science:

  • Optics and Photonics
  • Microfluidics
  • Materials Science

Background:

  • Microlens arrays (MLAs) are crucial in micro-optics for imaging, sensing, and displays.
  • Liquid MLAs offer advantages like smooth interfaces and tunability over solid counterparts.
  • Manufacturing precisely tunable liquid MLAs remains a significant technological challenge.

Purpose of the Study:

  • To demonstrate a novel and simple optofluidic method for fabricating tunable liquid MLAs.
  • To enable adjustable focusing and high-quality imaging using these liquid MLAs.
  • To explore their application in microparticle imaging and sensing.

Main Methods:

  • Fabrication of tunable liquid droplets that self-assemble into arrays.
  • Adjustment of droplet refractive index (RI) via flow rates to tune MLA focusing.
  • Integration of MLAs with a 4× objective for enhanced imaging.

Main Results:

  • Tunable focusing of liquid MLAs achieved with focal lengths ranging from 550 to 5370 μm.
  • Adjustable numerical apertures (NA) from 0.026 to 0.26.
  • Demonstrated improved resolution and magnification for microparticle imaging.

Conclusions:

  • The developed optofluidic method provides a simple, tunable, and high-performance solution for liquid MLA fabrication.
  • These tunable MLAs show great potential for adaptive imaging, sensing, and other micro-optical applications.
  • The ability to adjust both size and RI offers flexibility for diverse detection needs.