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Localization, Identification, and Excision of Murine Adipose Depots
Published on: December 4, 2014
Diagnosis and treatment of benign adipocytic tumors in children
Laura Daniela Pérez Daza1, Laura Camila González Villarreal2, Laura Camila Sánchez Rodríguez3
1Universidad Nacional de Colombia, Fundación Hospital Pediátrico la Misericordia, Av. Caracas # 1-65, 111411, Bogotá, DC, Colombia.
Insights
Pediatric benign adipocytic tumors, primarily lipomas, are common, often presenting as masses on lower limbs. Surgical resection is typically successful, with most children remaining asymptomatic post-treatment.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
- Dermatology
Background:
- Benign adipocytic tumors encompass a diverse range of neoplasms.
- Understanding their presentation in pediatric populations is crucial for diagnosis and management.
- These tumors can occur in various anatomical locations, posing diagnostic challenges.
Purpose of the Study:
- To delineate the demographic, clinical, diagnostic, and therapeutic characteristics of pediatric patients diagnosed with benign adipocytic tumors.
- To analyze data from a high-complexity teaching hospital over a 15-year period (2007-2021).
Main Methods:
- Retrospective observational descriptive study design.
- Data extracted from patient clinical records.
- Descriptive statistical analysis of qualitative and quantitative data.
Main Results:
- 76 pediatric patients were analyzed, with a mean age of 7.5 years; 60.5% were male.
- The most frequent symptom was a mass (73.7%), predominantly on lower limbs (23.6%).
- Lipoma (68.4%) and lipoblastoma (13.1%) were the most common histopathological diagnoses; 79.7% were asymptomatic at follow-up.
Conclusions:
- Benign adipocytic tumors represent a broad spectrum of pediatric neoplasms with varied presentations.
- This study enhances the understanding of clinical presentation and differential diagnosis for these rare tumors in children.
- Successful surgical resection is achievable, leading to favorable long-term outcomes.
Purpose:
To describe demographic, clinical, diagnostic and therapeutic aspects of pediatric patients with benign adipocytic tumors admitted to a high complexity teaching hospital from 2007 to 2021.
Methods:
Retrospective observational descriptive study. Patient information was retrieved from clinical records. A descriptive analysis was carried out for qualitative data and frequencies were calculated for quantitative data.
Results:
76 patients were included with a mean age of 7.5 years old where 60.5% were boys. The main symptom was a mass (73.7%) mostly found in the lower limbs (23.6%). Congenital birth defects were identified in 48.6% of the cases. Preoperative imaging was available in 78.9% of the patients allowing characterization of lesions or differential diagnosis. The therapeutic goal was resection with negative margins, which was feasible in all cases except for one case. The histopathological diagnosis was lipoma in 68.4% of the cases followed by lipoblastoma in 13.1%. The mean follow-up period was 17.9 months. 79.7% of the patients were asymptomatic at their last out-patient visit.
Conclusion:
Benign adipocytic tumors constitute a wide spectrum of lesions, which involve diverse anatomic segments from the neural axis to the inguinoscrotal region. The present work contributes to the general understanding of the clinical presentation and differential diagnosis for these infrequent neoplasms.
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