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Published on: January 28, 2014
Emerging biomarkers for the detection of cardiovascular diseases
Sreenu Thupakula1, Shiva Shankar Reddy Nimmala1, Haritha Ravula2
1Department of Biochemistry, Osmania University, Amberpet, Hyderabad, Telangana, 500007, India.
Insights
Cardiovascular disease (CVD) is a growing public health concern. Identifying novel biomarkers is crucial for early detection and improved diagnosis of CVD, including coronary and cerebrovascular diseases.
Area of Science:
- Biomedical Science
- Clinical Research
- Public Health
Background:
- Cardiovascular disease (CVD) prevalence is rising globally, posing a significant public health challenge.
- CVD cases spike annually, particularly impacting lower- and middle-income countries.
- Early detection of CVD is essential, necessitating the study of novel diagnostic biomarkers.
Purpose of the Study:
- To review and analyze current trends in cardiovascular disease (CVD) biomarker applications.
- To discuss the requirements for applying CVD biomarkers in various cardiovascular conditions.
- To highlight the importance of comprehensive biomarker expression analysis for cardiovascular illness.
Main Methods:
- Systematic literature review of medical journals, databases, and university library resources.
- Analysis of specific cardiovascular disease (CVD) markers and biomolecules.
- Compilation of existing clinical research on risk identification through biomarkers.
Main Results:
- A limited number of biomarkers have demonstrated reliability and utility in clinical practice.
- Biomarkers are valuable for predicting heart disease risk, diagnosis, and outcomes.
- The potential for single-molecule biomarkers in medicine is expected to significantly increase.
Conclusions:
- Current trends support the application of CVD biomarkers across diverse cardiovascular conditions like coronary heart disease and cerebrovascular disease.
- Establishing comprehensive biomarker expression is key for effective cardiovascular illness management.
- Further research into CVD biomarkers is vital for advancing diagnostic and prognostic capabilities.
Background:
The prevalence of cardiovascular disease (CVD) has been continuously increasing, and this trend is projected to continue. CVD is rapidly becoming a significant public health issue. Every year there is a spike in hospital cases of CVD, a critical health concern in lower- and middle-income countries. Based on identification of novel biomarkers, it would be necessary to study and evaluate the diagnostic requirements or CVD to expedite early detection.
Main Body:
The literature review was written using a wide range of sources, such as well-known medical journals, electronic databases, manuscripts, texts, and other writings from the university library. After that, we analysed the specific markers of CVD and compiled a systematic review. A growing body of clinical research aims to identify people who are at risk for cardiovascular disease by looking for biomolecules. A small number of biomarkers have been shown to be useful and reliable in medicine. Biomarkers can be used for a variety of clinical applications, such as predicting heart disease risk, diagnosing disease, or predicting outcomes. As a result of the ability for a single molecule to act as a biomarker, its usefulness in medicine is expected to increase significantly.
Conclusions:
Based on assessing the current trends in the application of CVD markers, we discussed and described the requirements for the application of CVD biomarkers in coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other cardiovascular illnesses. Furthermore, the current review focuses on biomarkers for CVD and the procedures that should be considered to establish the comprehensive nature of the expression of biomarkers for cardiovascular illness.
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