Portable ratiometric fluorescence analytical device for copper ions based on smartphone in environment and living...

The concentration of copper ions (Cu²⁺) in the environment is closely related to water quality, food, and biological health. As an indispensable metal element for the human body, its content is closely related to many diseases. However, the current detection methods for Cu²⁺ have some limitations, such as complicated operations and unfavorable on-site analysis. Therefore, this work constructs a novel ratiometric fluorescent probe (QLP), which has the advantages of rapid response, good anti-interference ability and high sensitivity. It has been successfully used for the detection of Cu²⁺ in water samples, soil, and food. In addition, low cytotoxicity and strong tissue penetration make it suitable for the detection of Cu²⁺ in living cells and zebrafish, offering a chemical tool for exploring the physiological and pathological processes related to Cu²⁺. It is important to use probe QLP and portable UV lamp to create an easy-to-operate Cu²⁺ detection platform, which can quickly detect Cu²⁺ on-site by combining with a smartphone. This work not only provides a detection tool for on-site analysis of Cu²⁺, but also provides a reference strategy for the development of on-site detection methods for other environmental pollutants.