Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tracheal autograft revascularization.

S C Balderman, G Weinblatt

    The Journal of Thoracic and Cardiovascular Surgery
    |September 1, 1987
    PubMed
    Summary

    Omental pedicle flaps failed to revascularize tracheal transplants, leading to graft failure. Further research is needed to find effective methods for tracheal allograft revascularization.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evaluation and treatment of carotid stenosis in open-heart surgery patients.

    The Journal of surgical research·1994
    Same author

    Cardioplegic arrest of the myocardium with calcium blocking agents.

    Journal of cardiovascular pharmacology·1992
    Same author

    Pharmacologic support of the myocardium following aortocoronary bypass surgery: a comparative study.

    Journal of clinical pharmacology·1986
    Same author

    Effect of vitamin D3 on imaging of experimental myocardial infarcts with technetium-99m pyrophosphate: further studies of the role of calcium.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1985
    Same author

    Comparison of ceftriaxone and cefazolin prophylaxis against infection in open heart surgery.

    American journal of surgery·1984
    Same author

    Preparation of venous allografts. A comparison of techniques.

    Annals of surgery·1984

    Area of Science:

    • Regenerative Medicine
    • Transplantation Biology
    • Surgical Innovation

    Background:

    • Tracheal transplantation requires robust revascularization for graft survival.
    • Omental pedicle flaps are a potential vascularized tissue source.

    Purpose of the Study:

    • To evaluate the efficacy of omental pedicle flaps for revascularizing tracheal homografts.
    • To assess chondrocyte viability and graft integrity post-transplantation.

    Main Methods:

    • Three experimental groups involving tracheal allografts and autografts embedded in omentum.
    • Assessment of graft transformation, malacia, stenosis, and chondrocyte viability.

    Main Results:

    • Grafts transformed into connective tissue tubes, indicating failure of revascularization.
    • Tracheal malacia and ring loss were observed in autograft groups.
    • Omental pedicle grafts did not sustain chondrocyte viability.

    Conclusions:

    • Omental pedicle flaps are insufficient for tracheal allograft revascularization.
    • A reliable method for tracheal transplant revascularization is yet to be established.

    Related Experiment Videos