Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

936
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
936
Proteins: Dietary Sources and Requirements01:28

Proteins: Dietary Sources and Requirements

566
Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
566
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

1.6K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
1.6K
Signs of Puberty01:27

Signs of Puberty

562
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
562
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

640
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
640
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.8K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Number and type of food additives in plant-based vs animal-based products: an analysis of a UK supermarket range.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment·2026
Same author

Dietary trends and the decline in male reproductive health.

Hormones (Athens, Greece)·2023
Same author

Low-carbohydrate diets and men's cortisol and testosterone: Systematic review and meta-analysis.

Nutrition and health·2022
See all related articles

Related Experiment Video

Updated: Aug 24, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.2K

High-protein diets and testosterone.

Joseph Whittaker1

  • 1The School of Allied Health and Community, University of Worcester, UK.

Nutrition and Health
|October 21, 2022
PubMed
Summary
This summary is machine-generated.

Very high-protein diets (>3.4g/kg/day) may decrease testosterone, but high- and moderate-protein diets (1.25-3.4g/kg/day) do not. This clarifies protein intake

Keywords:
Proteinandrogenshigh-protein dietmenprotein intaketestosterone

More Related Videos

Murine Prostate Micro-dissection and Surgical Castration
08:49

Murine Prostate Micro-dissection and Surgical Castration

Published on: May 11, 2016

46.0K
Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

888

Related Experiment Videos

Last Updated: Aug 24, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.2K
Murine Prostate Micro-dissection and Surgical Castration
08:49

Murine Prostate Micro-dissection and Surgical Castration

Published on: May 11, 2016

46.0K
Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

888

Area of Science:

  • Endocrinology
  • Sports Nutrition
  • Human Physiology

Background:

  • Recent meta-analysis linked low-carbohydrate, high-protein diets to decreased testosterone in men.
  • The term 'high-protein' lacks standardized definition, causing confusion in research interpretation.
  • Understanding protein intake thresholds is crucial for hormonal health in athletes and general population.

Approach:

  • Systematic review and meta-analysis of existing studies on diet and male hormone levels.
  • Proposed clear definitions for protein intake levels: very high (>3.4 g/kg/day), high (1.9-3.4 g/kg/day), moderate (1.25-1.9 g/kg/day), and low (<1.25 g/kg/day).
  • Analyzed the association between these defined protein intake levels and changes in total testosterone.

Key Points:

  • Diets exceeding 3.4 g/kg/day (very high protein) were associated with a decrease in total testosterone.
  • High-protein (1.9-3.4 g/kg/day) and moderate-protein (1.25-1.9 g/kg/day) diets showed no consistent negative impact on testosterone levels.
  • The majority of individuals, including athletes, consume protein amounts below the threshold linked to testosterone reduction.

Conclusions:

  • The definition of 'high-protein' intake is critical for accurate interpretation of its effects on male testosterone.
  • Very high protein intake (>3.4 g/kg/day) may negatively impact testosterone, while intakes within the high and moderate ranges do not.
  • Proposed definitions provide a clearer framework for future research on protein intake and hormonal health.