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Comparison of different bioglass applications on root caries - A laboratory-based study
Ahmed Sleibi1,2, Beliz Ozel3, Paul Anderson1
1Institute of Dentistry, Barts and The London, Queen Mary's School of Medicine and Dentistry, Turner Street, London, UK.
The Saudi Dental Journal
|October 21, 2022
Summary
Bioglass in toothpaste shows promise for reversing root caries. A 15% bioglass concentration significantly reduced surface roughness and arrested caries progression compared to lower concentrations and fluoride-only toothpaste.
Area of Science:
- Biomaterials Science
- Restorative Dentistry
- Cariology
Background:
- Root caries is a significant dental issue, particularly in aging populations.
- Bioglass has demonstrated remineralization potential in previous studies.
- Optimizing bioglass concentration for root caries treatment is crucial.
Purpose of the Study:
- To evaluate the efficacy of different bioglass concentrations in a prophylaxis paste for treating root caries in vitro.
- To assess the impact of bioglass on surface roughness and calcium ion release in carious tooth root surfaces.
Main Methods:
- An in vitro study using 90 extracted teeth with root caries.
- Teeth were treated with prophylaxis pastes containing 15% bioglass, 5% bioglass, or 1,450 ppm fluoride (control).
- Surface roughness was measured over 720 hours; calcium ion release and SEM analysis were also performed.
Main Results:
- The 15% bioglass group showed the most significant reduction in surface roughness (p=0.001).
- Calcium ion release was highest in the 5% bioglass group, while the control group showed the least release.
- SEM confirmed the presence of bioglass particles on samples treated with 15% bioglass.
Conclusions:
- A prophylaxis paste containing 15% bioglass effectively reduced surface roughness, indicating potential for root caries arrest.
- Higher bioglass concentrations may offer superior surface smoothing effects compared to lower concentrations or fluoride alone.
- Further clinical studies are warranted to confirm the therapeutic potential of bioglass in root caries management.

