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Bacterial Phylum Spirochaetes01:30

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Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
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Updated: Aug 24, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

4.9K

Spinal brucellosis causing spondylodiscitis.

Abdirahim Ali Adam1, Mohamed Sheikh Hassan2, Ahmed Adam Osman3

  • 1Department of Infectious Diseases, Mogadishu Somali Turkish Training and Research Hospital, Somalia.

Annals of Medicine and Surgery (2012)
|October 21, 2022
PubMed
Summary

Spinal brucellosis, a challenging zoonotic disease, can cause back pain and weakness. Early diagnosis and prolonged antibiotic treatment led to significant improvement in a Somali patient with spondylodiscitis.

Keywords:
BrucellosisChronic back painSpondylodiscitis

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Public Health

Background:

  • Brucellosis is a prevalent zoonotic disease in developing nations like Somalia, often presenting with non-specific symptoms.
  • Spinal involvement, including spondylodiscitis, is common but can be diagnostically challenging.
  • Brucellosis can affect multiple organs, with spinal and paravertebral muscle involvement being frequent.

Observation:

  • An 18-year-old male presented with chronic low back pain, fever, urinary difficulties, and progressive lower extremity weakness.
  • Lumbar MRI revealed spondylodiscitis, and serological tests confirmed Brucella infection.
  • The patient exhibited tenderness over the lumbar vertebra and mild weakness in the left lower limb.

Findings:

  • The patient was diagnosed with spinal brucellosis presenting as spondylodiscitis.
  • Treatment involved a 6-month course of doxycycline and rifampicin, with initial streptomycin.
  • Significant clinical improvement was observed within 3 months of treatment.

Implications:

  • Spinal brucellosis should be considered in the differential diagnosis of chronic back pain and neurological deficits in endemic regions.
  • Successful non-surgical management of spondylodiscitis is achievable with appropriate antibiotic therapy.
  • Prolonged treatment durations may be necessary for patients with severe physical conditions.