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Related Experiment Video

Updated: Aug 24, 2025

Colloidal Synthesis of Nanopatch Antennas for Applications in Plasmonics and Nanophotonics
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Colloidal Synthesis of Nanopatch Antennas for Applications in Plasmonics and Nanophotonics

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A Versatile Synthetic Pathway for Producing Mesostructured Plasmonic Nanostructures.

Sejung Kim1,2, Stephen Palani1,3, Fehmi Civitci1,3

  • 1Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA.

Small (Weinheim an Der Bergstrasse, Germany)
|October 21, 2022
PubMed
Summary

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Highly branched gold nanostructures with sharp tips show promise for surface-enhanced Raman scattering (SERS) sensing. A new method using carbon quantum dots enables tunable synthesis of these gold or gold-silver nanoparticles for enhanced SERS detection.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemistry

Background:

  • Highly branched gold (Au) nanostructures with sharp tips are ideal substrates for surface-enhanced Raman scattering (SERS)-based sensing.
  • Developing efficient synthetic routes for such nanostructures is crucial for advancing sensing technologies.

Purpose of the Study:

  • To present a simple synthetic route for producing Au or Au-Ag bimetallic mesostructured plasmonic nanoparticles (MSPNs) with multiple sharpened tips.
  • To investigate the influence of carbon quantum dots (CQDs) concentration, reaction temperature, and seed particles on MSPN morphology.
  • To evaluate the SERS activity of the synthesized MSPNs for detecting specific analytes.

Main Methods:

  • Synthesis of Au and Au-Ag bimetallic MSPNs using a novel method involving carbon quantum dots (CQDs).
Keywords:
bimetallic nanostructurescarbon quantum dotsgold nanocrystalsmesostructuressurface-enhanced Raman scattering

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  • Morphological control of MSPNs by adjusting CQD concentration, reaction temperature (25–80 °C), and seed particle parameters.
  • Characterization of MSPN properties and evaluation of their SERS performance using rhodamine 6G and methylene blue.

    • Main Results:

    • A simple synthetic route for Au and Au-Ag MSPNs with multiple sharpened tips was established.
    • MSPN morphology, including diameter (80–200 nm), was tunable by controlling CQD concentration (optimal molar ratio [HAuCl4]/[CQDs] ≈25) and reaction temperature.
    • Hierarchical MSPNs with multiple Au nanocrystals formed on seed particle surfaces.
    • Bimetallic MSPNs exhibited superior SERS sensitivity, detecting rhodamine 6G at 10⁻⁷ M and methylene blue at 10⁻⁶ M.

    Conclusions:

    • The developed synthetic process offers a controllable method for creating highly branched Au and Au-Ag MSPNs.
    • These MSPNs possess excellent SERS activity, particularly the bimetallic variants.
    • The synthesized MSPNs are promising candidates for highly sensitive SERS-based chemical sensing applications.