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GFAP astrocytopathy presenting with profound intracranial hypertension and vision loss
Ryan Canissario1, Lawrence Samkoff1, Maxime Junior Jean1
1Department of Neurology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, United States of America.
Background:
Glial fibrillary acidic protein (GFAP) astrocytopathy is a steroid-responsive autoimmune meningoencephalomyelitis commonly preceded by a viral illness. It is clinically characterized by encephalopathy, myelopathy and papillitis without significant effect on visual acuity. It can be associated with an underlying malignancy or autoimmune condition.
Objective:
To report a novel case of GFAP astrocytopathy presenting with profound intracranial hypertension and bilateral vision loss.
Methods:
Case report.
Results And Conclusion:
GFAP astrocytopathy should be considered when evaluating patients with intracranial hypertension or bilateral vision loss, particularly when other features of autoimmune encephalitis are present.
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