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Ocular findings in central precocious puberty

Serkan Bilge Koca1, Semra Koca2

  • 1Department of Pediatrics, Division of Pediatric Endocrinology, Kayseri City Education and Research Hospital, Kayseri, Turkey.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|October 21, 2022
PubMed

Insights

Children with central precocious puberty (PP) show increased axial length (AL) and choroidal thickness (ChT). These ocular findings were higher compared to healthy controls, indicating potential long-term effects.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Endocrinology

Background:

  • Central precocious puberty (PP) is a condition where puberty begins early.
  • Ocular changes associated with PP require further investigation.

Purpose of the Study:

  • To evaluate ocular findings in children with central precocious puberty (PP).

Main Methods:

  • Prospective study of 38 children with PP and 34 controls.
  • Ocular parameters measured: refractive error, axial length (AL), anterior segment parameters (keratometry, corneal volume, anterior chamber depth/volume, iridocorneal angle), central macular thickness (CMT), retinal nerve fiber layer (RNFL) thickness, and subfoveal choroidal thickness (ChT).
  • Correlation with Tanner stage analyzed in the PP group.

Main Results:

  • Children with PP had less hyperopic spherical refraction and significantly higher AL compared to controls.
  • AL and spherical value correlated significantly with Tanner stage.
  • Subfoveal choroidal thickness (ChT) was significantly higher in the PP group, irrespective of Tanner stage.
  • No significant differences were found in anterior segment parameters, CMT, or RNFL thickness between groups.

Conclusions:

  • Children with central PP exhibit higher axial length (AL) and choroidal thickness (ChT) compared to those without PP.
  • These findings suggest potential ocular structural differences in children with central PP.
Abstract

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