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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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The ABO Blood Group01:12

The ABO Blood Group

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The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
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Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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The effects of additive solutions on the development of storage lesions in stored canine platelet concentrates.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2020
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Updated: Aug 24, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Laboratory Testing in Transfusion Medicine.

Katherine Jane Wardrop1, Elizabeth Brooks Davidow1

  • 1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610, USA.

The Veterinary Clinics of North America. Small Animal Practice
|October 21, 2022
PubMed
Summary

Veterinary transfusion medicine relies on laboratory testing for donor screening and compatibility to prevent adverse reactions. Diagnostic tests are crucial for managing potential transfusion reactions in dogs and cats.

Keywords:
Blood typingCrossmatchingTRACS guidelinesTransfusion reactions

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Area of Science:

  • Veterinary Medicine
  • Transfusion Medicine
  • Laboratory Diagnostics

Background:

  • Canine and feline transfusions are increasingly common life-saving procedures.
  • Laboratory testing is essential for safe and effective veterinary transfusion practices.
  • Transfusion reactions can occur if proper screening and testing are not performed.

Purpose of the Study:

  • To highlight the critical role of laboratory testing in veterinary transfusion medicine.
  • To emphasize the importance of donor screening and pretransfusion compatibility testing.
  • To outline the diagnostic approach for managing transfusion reactions in animals.

Main Methods:

  • Review of laboratory testing protocols for donor screening.
  • Discussion of pretransfusion blood typing and crossmatching techniques.
  • Overview of diagnostic methods for identifying transfusion reactions.

Main Results:

  • Laboratory tests effectively screen donors for health and pathogens.
  • Pretransfusion typing and compatibility testing significantly reduce immunologic reactions.
  • Diagnostic tests aid in tailoring therapy for transfusion reactions.

Conclusions:

  • Comprehensive laboratory testing is fundamental to safe canine and feline transfusions.
  • Implementing robust screening and compatibility testing protocols minimizes transfusion risks.
  • Prompt diagnosis and appropriate testing are key to managing adverse events in transfusion medicine.