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Updated: Aug 24, 2025

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle
Anthony Roylance1, Stefan Spinty2, Benedetta Pettorini3
1Department of Neurosurgery, Alder Hey Children's Charity NHS Foundation Trust, Liverpool, England, UK. Anthony3484@doctors.org.uk.
Abstract:
Multi-systemic smooth muscle dysfunction syndrome (MSMDS) is extremely rare and can manifest in multiple ways. Associated hydrocephalus has not yet been reported. Here, we report a three-year-old girl with communicating hydrocephalus and raised intracranial pressure secondary to MSMDS. Pathological mechanisms are proposed, as is the need to investigate patients diagnosed with MSMDS for ventriculomegaly and raised pressure.
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