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Cardiopulmonary exercise testing for patients with anorexia nervosa: a case-control study
Makoto Yamashita1, Keisuke Kawai2,3, Kenta Toda1,4
1Department of Psychosomatic Medicine, Kyushu University Hospital, Fukuoka, Japan.
Eating and Weight Disorders : EWD
|October 22, 2022
Summary
Patients with anorexia nervosa have significantly lower exercise tolerance, indicated by a lower anaerobic threshold (AT) and AT-METS compared to healthy individuals. This suggests a need for light-intensity aerobic exercise prescriptions for those with AN.
Area of Science:
- Cardiopulmonary exercise testing
- Eating disorder research
- Clinical exercise physiology
Background:
- Current eating disorder guidelines lack specific exercise intensity criteria.
- Anorexia nervosa (AN) patients require tailored physical activity management.
- Cardiopulmonary exercise testing (CPX) can assess exercise tolerance.
Purpose of the Study:
- To evaluate exercise tolerance in patients with anorexia nervosa (AN) using CPX.
- To compare the anaerobic threshold (AT) and AT-METS between AN patients and healthy controls (HC).
- To identify factors influencing exercise tolerance in AN patients.
Main Methods:
- CPX was conducted on 14 female AN patients and 14 HC.
- Anaerobic threshold (AT) and AT-METS were determined and compared.
- Factors like BMI, age, and heart rate response (ΔHR) were analyzed in the AN group.
Main Results:
- AN patients exhibited significantly lower AT (10.0 ml/kg/min) compared to HC (15.2 ml/kg/min).
- AT-METS was significantly lower in AN patients (2.9) versus HC (4.4).
- Heart rate response (ΔHR) was a key factor influencing AN-AT.
Conclusions:
- Patients with AN demonstrate reduced exercise capacity compared to healthy individuals.
- Findings support prescribing light-intensity aerobic exercise for AN patients.
- This research can inform future physical activity guidelines for AN treatment.
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