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Updated: Aug 24, 2025

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
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Review: Emergomycosis.

Denasha L Reddy1, Jeremy Nel2, Nelesh P Govender3

  • 1Division of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.

Journal De Mycologie Medicale
|October 22, 2022
PubMed
Summary
This summary is machine-generated.

Emergomycosis is a fungal infection primarily affecting immunocompromised individuals. While Emergomyces pasteurianus is widespread, Emergomyces africanus causes severe disease in Southern Africa, particularly in advanced HIV patients.

Keywords:
Dimorphic fungiEmergomycesEmergomycosisEmmonsiaEndemic mycosesMycosisSkin infection

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Immunocompromised Host Research

Background:

  • Emergomycosis is a disseminated clinical disease caused by dimorphic fungi in the genus Emergomyces.
  • It primarily affects individuals with compromised immune systems.

Purpose of the Study:

  • To provide a clinical overview of emergomycosis.
  • To discuss the taxonomy, epidemiology, pathogenesis, immunology, clinical features, diagnosis, therapy, and prognosis of emergomycosis.

Main Methods:

  • Literature review of existing research on emergomycosis.
  • Synthesis of information on fungal classification, disease spread, infection mechanisms, immune responses, clinical presentation, diagnostic methods, and treatment outcomes.

Main Results:

  • Emergomyces pasteurianus is the most geographically widespread species.
  • Emergomyces africanus is endemic to Southern Africa and causes disseminated disease with cutaneous involvement in advanced HIV patients.

Conclusions:

  • Emergomycosis is a significant opportunistic infection in immunocompromised patients.
  • Further research is required to improve understanding of pathophysiology, diagnosis, and management of emergomycosis.