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Published on: January 28, 2020
[Prognostic impact of cardiovascular risk factors in patients admitted for acute coronary syndrome]
J E Puche1, M Iturregui-Guevara2, R Vázquez3
1Servicio de Cardiología, Hospital Universitario Puerta del Mar, Cádiz, España; Servicio de Cardiología, Hospital Costa del Sol, Marbella, España.
Insights
Improving control of cardiovascular risk factors (CVRF) significantly benefits patients post-acute coronary syndrome. Poorly controlled CVRF, especially hypertension, increases major adverse cardiovascular events, highlighting the need for enhanced prevention strategies.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Context:
- Cardiovascular prevention focuses on controlling cardiovascular risk factors (CVRF).
- Recent studies show disappointing outcomes despite prevention efforts.
- The impact of CVRF control on post-acute coronary syndrome prognosis requires further analysis.
Purpose:
- To analyze the impact of different CVRFs and their control levels on patient prognosis after acute coronary syndrome.
- To identify specific CVRFs with the greatest impact on cardiovascular events.
Summary:
- A study of 1,689 acute coronary syndrome patients revealed predominantly male participants with obesity, smoking history, and poor CVRF control (hypertension, diabetes, dyslipidemia).
- Underutilization of beneficial drugs for CVRF management was noted.
- A direct correlation exists between the number of CVRFs and major adverse cardiovascular events at 2 years, with hypertension being the most impactful.
- The SARS-CoV-2 lockdown negatively affected CVRF control and cardiovascular outcomes.
Impact:
- Findings underscore the potential for prognostic improvement through better CVRF control in ischemic heart disease patients.
- Highlights the critical need for implementing effective cardiovascular prevention campaigns.
Introduction And Objectives:
Cardiovascular prevention measures place the emphasis on controlling cardiovascular risk factors (CVRF). However, the most recent studies provide disappointing data, the impact of which remains to be determined. The objective of this study was to analyse the impact that the different CVRFs, and their degree of control, have on the prognosis of patients after acute coronary syndrome.
Patients And Methods:
Epidemiological, pharmacological, and CVRF control data were collected from 1,689 consecutive patients admitted from 2018 to 2020 for acute coronary syndrome to a tertiary hospital. Finally, the rate of major adverse cardiovascular events was calculated.
Results:
The patients admitted for acute coronary syndrome were predominantly men, with body mass index>25Kg/m2, smokers (or former smokers) and with poor CVRF control (50% for hypertension and diabetes and 35% for dyslipidaemia), especially those patients with a personal history of ischaemic heart disease. An underutilisation of useful drugs for CVRF control was found. A directly proportional relationship was observed between the number of CVRFs (or their poor control) and the incidence of major adverse cardiovascular events at 2 years, hypertension being the factor with the greatest cardiovascular impact. The SARS-CoV-2 lockdown worsened the degree of CVRF control and cardiovascular prognosis.
Conclusion:
There is still room for improvement in the control of CVRF, which would translate into a prognostic benefit for patients with ischaemic heart disease. The implementation of cardiovascular prevention campaigns seems essential.
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