Calcium in the mitochondria following brief ischemia of gerbil brain

Calcium was localized in neurons and glial cells of the CA1 region of hippocampus and in neurons of parietal cortex with the oxalate-pyroantimonate electron cytochemical method following recovery from 5-min ischemia of gerbil brain. During the early postischemic recirculation phase a maximum amount of calcium deposits was detected in mitochondria of all investigated cells. A second rise in mitochondrial calcium deposits was observed in parallel with the onset of ultrastructural degeneration of mitochondria and the loss of cellular integrity beginning 6 h postischemia.