Related Experiment Video
Updated: Aug 24, 2025

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
Oral Squamous Cell Carcinoma Metastasizing to the Heart: A Case Report from Taiwan
Jhe-Yuan Hsu1, Hsuan-Yu Lin2, Yuan-Po Yang3,4,5
1Division of General Practice, Department of Medical Education, Changhua Christian Hospital, Changhua, Taiwan.
Background:
The most common sites for metastasis from head and neck cancers are the lungs, bones, and liver. We present a rare case of squamous cell carcinoma of the buccal mucosa that metastasized to the right ventricle, pericardium, and bilateral lungs.
Methods:
A 61-year-old man with oral squamous cell carcinoma (cT4aN2cM0) exhibited mass-like echogenicity adhering to the right ventricular free wall that was accidentally discovered after concurrent chemoradiotherapy. A biopsy of the mass confirmed the oral origin of the metastasis.
Results:
The patient received palliative care and died 1 month after being diagnosed with cardiac involvement.
Conclusion:
Cardiac involvement is often not assessed because of its low prevalence. Cardiac metastasis should be considered in patients with malignancies presenting with nonspecific cardiac symptoms.
More Related Videos
10:19Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019