Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radical Oxidation of Allylic and Benzylic Alcohols01:21

Radical Oxidation of Allylic and Benzylic Alcohols

2.1K
Activated manganese(IV) oxide can selectively oxidize allylic and benzylic alcohols via a radical intermediate mechanism. Primary allylic alcohols are oxidized to aldehydes, while secondary allylic alcohols yield ketones. The redox reaction of potassium permanganate with an Mn(II) salt such as manganese sulfate (under either alkaline or acidic conditions), followed by thorough drying, yields the oxidizing agent: activated MnO2. While MnO2 is insoluble in the solvents used for the reaction, the...
2.1K
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

3.4K
Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
3.4K
Reduction of Alkenes: Catalytic Hydrogenation02:13

Reduction of Alkenes: Catalytic Hydrogenation

12.4K
Alkenes undergo reduction by the addition of molecular hydrogen to give alkanes. Because the process generally occurs in the presence of a transition-metal catalyst, the reaction is called catalytic hydrogenation.
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...
12.4K
Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate02:21

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate

12.6K
Alkenes can be dihydroxylated using potassium permanganate.  The method encompasses the reaction of an alkene with a cold, dilute solution of potassium permanganate under basic conditions to form a cis-diol along with a brown precipitate of manganese dioxide.
12.6K
The Supercomplexes in the Crista Membrane01:41

The Supercomplexes in the Crista Membrane

2.6K
The mitochondrial cristae membrane is the primary site for the oxidative phosphorylation (OXPHOS) process of energy conversion mediated through respiratory complexes I to V. These complexes have been widely studied for decades, and it has been proven that they form supramolecular structures called respiratory supercomplexes (SC). These higher-order complexes may be crucial in maintaining the biochemical structure and improving the physiological activity of the individual complexes while...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structure-activity relationships of ATCUN-based Cu(II) complexes with large chelate rings: interplay of ROS generation, DNA binding, and nuclease activity.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Platelet-Released Growth Factors (PRGFs) Activate NRF2-ARE and Modulate Inflammatory Response in an NRF2-Dependent Manner in Primary Human Keratinocytes.

Journal of cosmetic dermatology·2025
Same author

Fully Oxidized State of the Oxygen-Tolerant [NiFe] Hydrogenase from <i>Hydrogenophilus thermoluteolus</i> SH: A Quantum Mechanics Cluster and Quantum Mechanics/Molecular Mechanics Study.

Inorganic chemistry·2025
Same author

Molecular Recognition and Chiral Discrimination from NMR and Multi-Scale Simulations.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

The structural integrity of human TFF1 under reducing conditions.

Redox biology·2025
Same author

Fullerene-Doped Poly(ionic liquids) as Small Molecular Gas Sensors-Control of Intermolecular Interactions.

ACS omega·2025

Related Experiment Video

Updated: Aug 24, 2025

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
08:40

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

3.7K

Mononuclear manganese complexes as hydrogen evolving catalysts.

Vishakha Kaim1, Meenakshi Joshi2, Matthias Stein2

  • 1Department of Chemistry, University of Delhi, Delhi, India.

Frontiers in Chemistry
|October 24, 2022
PubMed
Summary
This summary is machine-generated.

Manganese catalysts effectively generate molecular hydrogen (H2) from acidic solutions, offering a sustainable alternative to platinum. Researchers explored novel manganese complexes, optimizing ligand design for efficient hydrogen production.

Keywords:
bioinorganic chemistrycomputational catalysishydrogen evolutionhydrogenasemanganese catalystreaction mechanismredox activity

More Related Videos

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
05:47

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts

Published on: August 7, 2018

7.8K
A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions
06:32

A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions

Published on: August 17, 2016

19.7K

Related Experiment Videos

Last Updated: Aug 24, 2025

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
08:40

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

3.7K
Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
05:47

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts

Published on: August 7, 2018

7.8K
A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions
06:32

A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions

Published on: August 17, 2016

19.7K

Area of Science:

  • Inorganic Chemistry
  • Catalysis
  • Renewable Energy

Background:

  • Molecular hydrogen (H2) is crucial for future non-fossil energy, with platinum catalysts dominating hydrogen generation.
  • Biological hydrogenase enzymes inspire the search for alternative, non-precious metal catalysts.
  • Manganese, known for oxygen reduction, is underexplored for proton reduction in acidic media.

Purpose of the Study:

  • To synthesize, characterize, and evaluate novel mono-nuclear Mn(I) complexes for catalytic hydrogen evolution.
  • To investigate the impact of ligand variation on catalytic performance, including turnover frequencies and overpotentials.
  • To elucidate reaction mechanisms using quantum chemical studies and electrochemical analysis.

Main Methods:

  • Synthesis and characterization of four mono-nuclear Mn(I) complexes.
  • Electrochemical studies (UV-Vis, cyclic voltammetry) to assess catalytic activity.
  • Quantum chemical calculations to interpret spectral data and rationalize reaction mechanisms.

Main Results:

  • All four synthesized Mn(I) complexes demonstrated catalytic activity in reducing protons to H2 in acidic media.
  • Ligand modifications influenced turnover frequencies and overpotentials, demonstrating control over catalytic efficiency.
  • Quantum chemical studies confirmed structural changes during redox events and identified key mechanistic steps for H2 release.

Conclusions:

  • Novel manganese complexes are effective catalysts for the hydrogen evolution reaction (HER).
  • Ligand design is critical for tuning the performance of manganese-based HER catalysts.
  • This study expands the scope of elements for HER catalysis, highlighting manganese as a promising alternative to platinum.