Related Experiment Video
Updated: Aug 24, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
Published on: September 20, 2024
Statistical model for factors correlating with COVID-19 deaths
Mikko Nuutinen1, Ira Haavisto2, Antti J Niemi3
1NHG Finland and University of Helsinki, Finland.
Background:
The COVID-19 pandemic has caused major disruption in societies globally. Our aim is to understand, what factors were associated with the impact of the pandemic on death rates. This will help countries to better prepare for and respond in future pandemics.
Methods:
We modeled with a linear mixed effect model the impact of COVID-19 with the dependent variable "Daily mortality change" (DMC) with country features variables and intervention (containment measurement) data. We tested both country characteristics consisting of demographic, societal, health related, healthcare system specific, environmental and cultural feature as well as COVID-19 specific response in the form of social distancing interventions.
Results:
A statistically significant country feature was Geert Hofstede's masculinity, i.e., the extent to which the use of force is endorsed socially, correlating positively with a higher DMC. The effects of different interventions were stronger that those of country features, particularly cancelling public events, controlling international travel and closing workplaces.
Conclusion:
Social distancing interventions and the country feature: Geert Hofstede's masculinity dimension had a significant impact on COVID-19 mortality change. However other country features, such as development and population health did not show significance. Thus, the crises responders and scholars could revisit the concept and understanding of preparedness for and response to pandemics.
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Correlation
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
Causality in Epidemiology
Steps in Outbreak Investigation

