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Updated: Aug 24, 2025

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
Second-degree burn induced by high-concentration topical capsaicin with mobility sequelae: A case report
Kilian Trin1,2, Justine Perino1,3, Marion Allouchery3,4,5
1Service de Pharmacologie Médicale, Centre Régional de Pharmacovigilance de Bordeaux, CHU de Bordeaux, Bordeaux, France.
Abstract:
High-concentration topical capsaicin is used as a second-line treatment for neuropathic pain. Transient, mild burning sensation and erythema are expected adverse drug reactions. Here, we report the first case of second degree burn after the application of a high-concentration topical capsaicin patch with secondary mobility sequelae. Nine months after the application, neuropathic pain still remained and the patient described mobility difficulties in daily activities, preventing her from returning to work. This report aims to raise the question of the benefit/risk ratio of high concentration topical capsaicin.
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