Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

4.4K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.4K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.8K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Different Mutational Profiles of Subcutaneous Panniculitis-like T-cell Lymphoma and Lupus Panniculitis: An Additional Case Series.

Actas dermo-sifiliograficas·2024
Same author

Different Mutational Profiles of Subcutaneous Panniculitis-like T-cell Lymphoma and Lupus Panniculitis: An Additional Case Series.

Actas dermo-sifiliograficas·2024
Same author

Subcutaneous panniculitis-like T-cell lymphoma and lupus erythematosus profundus: a diagnostic dilemma.

BMJ case reports·2024
Same author

Classifications of cutaneous lymphomas and lymphoproliferative disorders: An update from the EORTC cutaneous lymphoma histopathology group.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Transformations of marginal zone lymphomas and lymphoplasmacytic lymphomas: Report from the 2021 SH/EAHP Workshop.

American journal of clinical pathology·2023
Same author

Transdifferentiation, phenotypic infidelity, progression, and transformation in T/NK-cell neoplasms: Report from the 2021 SH/EAHP Workshop.

American journal of clinical pathology·2023

Related Experiment Video

Updated: Aug 24, 2025

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.6K

Recent advances in cutaneous lymphoma-implications for current and future classifications.

J R Goodlad1, L Cerroni2, S H Swerdlow3

  • 1Department of Pathology, NHS Greater Glasgow and Clyde, Level 3 Laboratory Medicine Building Queen Elizabeth University Hospital, 1345 Govan Rd, Glasgow, G51 4TF, UK. john.goodlad@ggc.scot.nhs.uk.

Virchows Archiv : an International Journal of Pathology
|October 24, 2022
PubMed
Summary

The 2022 International Consensus Classification refines primary cutaneous lymphoma diagnoses. It reclassifies certain lymphomas, like primary cutaneous marginal zone lymphoma, as indolent lymphoproliferative disorders, reflecting new biological insights.

Keywords:
ClassificationCutaneousLymphomaLymphoproliferative disorder

More Related Videos

Enhancing Tumor Content through Tumor Macrodissection
10:04

Enhancing Tumor Content through Tumor Macrodissection

Published on: February 12, 2022

10.5K
Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
07:52

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

19.9K

Related Experiment Videos

Last Updated: Aug 24, 2025

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.6K
Enhancing Tumor Content through Tumor Macrodissection
10:04

Enhancing Tumor Content through Tumor Macrodissection

Published on: February 12, 2022

10.5K
Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
07:52

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

19.9K

Area of Science:

  • Hematology
  • Oncology
  • Dermatology

Background:

  • The classification of mature lymphoid neoplasms has evolved through international consensus, notably the WHO classifications.
  • Primary cutaneous lymphomas were integrated following the 2005 WHO-EORTC classification.
  • Refinement of diagnostic criteria and studies for primary cutaneous lymphoma remains ongoing.

Purpose of the Study:

  • To summarize the 2022 International Consensus Classification for primary cutaneous lymphomas.
  • To highlight major changes in classification and new biological insights.
  • To provide an overview of entities presenting primarily in the skin.

Main Methods:

  • Review and synthesis of the 2022 International Consensus Classification.
  • Analysis of recent biological studies on primary cutaneous lymphomas.
  • Comparison with previous classification systems (WHO, WHO-EORTC).

Main Results:

  • Primary cutaneous marginal zone lymphoma is now a lymphoproliferative disorder, with two subtypes identified.
  • Primary cutaneous acral CD8 positive T cell lymphoma is also classified as a lymphoproliferative disorder.
  • New biological insights reveal genetic, epigenetic, and transcriptional changes.

Conclusions:

  • The 2022 classification reflects a more conservative approach to certain cutaneous lymphomas.
  • Recent biological discoveries enhance understanding and may guide novel therapies.
  • Further research is needed to clarify the categorization of cutaneous lymphomas and their relation to extracutaneous counterparts.