Related Experiment Video
Updated: Aug 24, 2025
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Physicochemical and Biological Properties of AH Plus Bioceramic
Letícia Chaves de Souza1, Glaucia Schuindt Teixeira Neves2, Timothy Kirkpatrick3
1Department of Endodontics, University of Texas Health Science Center at Houston, School of Dentistry at Houston, Houston, Texas; Center for Craniofacial Research, University of Texas School of Dentistry at Houston, Houston, Texas.
Introduction:
The purpose of this study was to evaluate the physicochemical and biological properties of AH Plus Bioceramic (AHPB; Dentsply Sirona, Charlotte, NC) in comparison to AH Plus (AHP, Dentsply Sirona) and EndoSequence BC Sealer (BC; Brasseler, Savannah, GA).
Methods:
The setting time, radiopacity, flow, solubility, calcium ion release, and pH were evaluated following ISO guidelines. Surface characterization and chemical constitution were evaluated by scanning electron microscopy/energy-dispersive X-ray spectroscopy. The antibacterial effect was tested against Enterococcus faecalis. Sealer cytotoxicity was tested using the XTT cell viability assay. Analysis of variance, Tukey, and unpaired t tests were used with a significance level of 5%.
Results:
The initial setting time of AHPB was shorter than AHP and BC (P ≤ .0001), whereas AHP showed a shorter final setting time (P ≤ .0001). AHPB was more radiopaque than BC (P = .0012) but less radiopaque than AHP (P = .0001). AHPB was more soluble than AHP (P ≤ .0001), whereas no difference was observed between AHPB and BC (P > .05). Immersion in phosphate-buffered saline decreased the solubility of AHPB and BC (P ≤ .005). AHPB calcium ion release was higher than AHP (P ≤ .05) but less than BC (P ≤ .0001). AHPB had the highest flow followed by AHP and BC (P > .05). All sealers were alkaline and able to eradicate E. faecalis. Surface morphology and chemical composition of all sealers changed after immersion in water and phosphate-buffered saline. Cell viability for AHPB and BC was higher than AHP (P ≤ .0001).
Conclusions:
AHPB presented adequate properties to be considered a good sealer, however, the high solubility may negatively impact the quality of the obturation.
Related Concept Videos
01:22Factors Influencing Drug Absorption: Physicochemical Parameters
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
01:17Mortar Properties
01:29Biofilms