Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hallucinogens and Psychedelics

Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Stimulants

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Are "race-neutral" lung volume prediction equations appropriate? A critical review of the contributions of anthropometric differences and socioeconomic factors to lung volumes.

The European respiratory journal·2026

Same author

Assessment of uranium with toxicological and radiological implications in potable water sources of the eastern region of Kumaun Himalaya, India.

Isotopes in environmental and health studies·2026

Same author

Water parks, vaping, COPD topics on team management, exacerbations, bronchoscopic therapies, lung transplantation, and artificial intelligence.

Current opinion in pulmonary medicine·2026

Same author

Ability of Radiomics Versus Humans in Predicting First-Pass Effect After Endovascular Treatment in the ESCAPE-NA1 Trial.

Stroke (Hoboken, N.J.)·2026

Same author

Chronic obstructive pulmonary disease exacerbations for the academic hospitalist: an opportunity to learn and improve care.

Current opinion in pulmonary medicine·2025

Same author

Understanding radon behaviour in traditional Indian dwellings: Insights from a validated CFD study of a representative mud test house.

Environmental pollution (Barking, Essex : 1987)·2025

Search research articles

Related Experiment Video

Updated: Aug 24, 2025

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

Marijuana and the Lung: Evolving Understandings.

Manish Joshi¹, Anita Joshi², Thaddeus Bartter¹

¹Pulmonary and Critical Care Division, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA; Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.

The Medical Clinics of North America

|October 24, 2022

Summary

This summary is machine-generated.

Marijuana

Keywords:

Cannabis smoking Chronic obstructive pulmonary disease Lung cancer Marijuana

More Related Videos

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Administration of Δ⁹-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

Related Experiment Videos

Last Updated: Aug 24, 2025

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Administration of Δ⁹-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

Area of Science:

Neuroscience and Pharmacology
Pulmonary Medicine

Background:

Cannabinoid receptors are widespread in the human brain, influencing nervous system functions.
Historical use of marijuana products is well-documented.

Purpose of the Study:

To explore the impacts of cannabinoids on diseases like pain and seizures.
To evaluate the respiratory and cognitive effects of marijuana use.

Main Methods:

Review of existing literature on cannabinoid receptor distribution.
Analysis of studies investigating marijuana's effects on the respiratory system and cognitive functions.

Main Results:

Cannabinoids influence symptoms such as pain and seizures.
Marijuana use is linked to bronchitis but not chronic obstructive pulmonary disease or lung cancer.
Potential for cognitive impairment and developmental brain effects exists.

Conclusions:

Cannabinoids have significant neurological effects, impacting conditions like pain and seizures.
While marijuana poses risks like bronchitis and potential cognitive impairment, it differs from tobacco regarding lung cancer and COPD.
Further research is needed to balance the therapeutic potential of marijuana with its risks, especially concerning the developing brain.