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Published on: August 8, 2020
Full thickness skin graft versus split thickness skin graft in paediatric patients with hand burns: Systematic review
Abdulmalik Alsaif1, Mohammad Karam2, Amrit Hayre3
1MBChB, Walsall Healthcare NHS Trust, West Midlands, UK.
Insights
Full thickness skin grafts significantly reduce contractures and surgical releases in pediatric hand burns compared to split thickness grafts. While split thickness grafts offer better cosmetic outcomes, full thickness grafts provide superior functional results.
Area of Science:
- Reconstructive surgery
- Pediatric burn care
- Wound healing
Background:
- Hand burns in children present unique challenges for reconstructive surgery.
- Grafting techniques, including full thickness skin grafts (FTSG) and split thickness skin grafts (STSG), are crucial for optimal outcomes.
- Comparing FTSG and STSG in pediatric hand burns is essential for guiding clinical practice.
Approach:
- A systematic review and meta-analysis adhering to PRISMA guidelines was conducted.
- Electronic searches identified randomized controlled trials and non-randomized studies comparing FTSG and STSG in pediatric hand burn patients.
- Fixed effects modeling was applied for data analysis.
Key Points:
- FTSG demonstrated a statistically significant reduction in post-graft contracture and the need for subsequent surgical release compared to STSG.
- FTSG showed superior post-operative functional ability in pediatric hand burn patients.
- STSG resulted in better scar, aesthetic, and color assessments, with less observed hair growth.
Conclusions:
- FTSG represent a superior alternative to STSG for pediatric hand burns, primarily due to reduced contracture formation and fewer required surgical interventions.
- While STSG may offer cosmetic advantages, the functional benefits and reduced complication rates of FTSG make them preferable in this patient population.
- Further research may explore optimizing FTSG techniques to mitigate their cosmetic limitations.
Abstract:
Our objective was to compare the outcomes of full thickness skin grafts versus split thickness skin grafts in paediatric hand burn patients. A systematic review and meta-analysis were carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) Guidelines, and an electronic search was conducted to identify all Randomised Controlled Trials and non-randomised studies comparing the outcomes of full thickness skin grafts versus split thickness skin grafts in paediatric hand burn patients. Primary outcomes included development of post-graft contracture and the necessity for surgical release. Secondary outcomes consisted of evaluation of function, cosmesis and colour, scar and feeling, hair growth, and other complaints. For the analysis, fixed effects modelling was applied. Results: ten non-randomised trials with a total of 532 grafts were found. Full thickness skin grafts exhibited a statistically significant decrease in the development of post-graft contracture (Odds Ratio [OR] = 0.35, P = 0.0001) and later surgical releases (OR = 0.06, P = 0.00001). For secondary outcomes, full thickness skin grafts outperformed split thickness skin grafts in post-operative functional ability. However, split thickness skin grafts, showed to be superior in scar, aesthetic, and colour assessments, and less hair growth was observed for split thickness skin grafts. No significant difference was seen in sensation and donor or recipient site complaints. Overall, full thickness skin grafts are a better alternative for paediatric hand burns than split thickness skin transplants because they are linked with reduced post-graft contracture and the requirement for surgical release.
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