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Updated: Aug 24, 2025

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Improvement in sagittal alignment and mechanical low-back pain following deep brain stimulation for Parkinson's
Jaime R Guerrero1, Lokeshwar S Bhenderu1, Khaled M Taghlabi1
1Departments of1Neurological Surgery and.
Background:
Parkinson's disease (PD) is a common neurogenerative disease marked by the characteristic triad of bradykinesia, rigidity, and tremor. A significant percentage of patients with PD also demonstrate postural abnormalities (camptocormia) that limit ambulation and accelerate degenerative pathologies of the spine. Although deep brain stimulation (DBS) is a well-established treatment for the motor fluctuations and tremor seen in PD, the efficacy of DBS on postural abnormalities in these patients is less clear.
Observations:
The authors present a patient with a history of PD and prior lumbosacral fusion who underwent bilateral subthalamic nucleus DBS and experienced immediate improvement in sagittal alignment and subjective relief of mechanical low-back pain.
Lessons:
DBS may improve postural abnormalities seen in PD and potentially delay or reduce the need for spinal deformity surgery.
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