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Psychiatric morbidity among men using anabolic steroids
Josefine Windfeld-Mathiasen1, Thea Christoffersen1, Niels August Willer Strand1
1Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
Depression and Anxiety
|October 25, 2022
Summary
Men abusing anabolic steroids show significantly higher rates of psychiatric conditions, including anxiety, psychosis, and depression. This association persists even after accounting for socioeconomic factors, highlighting a critical public health concern.
Area of Science:
- Psychiatry
- Endocrinology
- Public Health
Background:
- Anabolic-androgenic steroid (AAS) abuse is prevalent among athletes and bodybuilders.
- AAS use is linked to various physical health issues, but psychiatric effects require further investigation.
Purpose of the Study:
- To investigate the association between anabolic steroid abuse and psychiatric morbidity in men.
- To determine if socioeconomic factors influence the relationship between AAS use and mental health outcomes.
Main Methods:
- Retrospectively matched cohort study design.
- Inclusion of 545 males with positive anabolic steroid tests and 5450 matched controls.
- Data linkage with national registers for psychiatric comorbidity and socioeconomic factors.
Main Results:
- Significantly increased incidence of anxiolytic and antipsychotic prescriptions post-sanction (HR: 2.34 and 2.69, respectively).
- Elevated prevalence and incidence of antidepressant use among AAS users, both before and after sanction (HR: 1.65).
- Statistical significance maintained after controlling for socioeconomic status.
Conclusions:
- Anabolic steroid abuse is strongly associated with increased psychiatric morbidity.
- AAS users exhibit higher risks for anxiety, psychosis, and depression.
- The findings underscore the need for mental health support for individuals misusing anabolic steroids.
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