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Updated: Aug 24, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Application of hybrid cranioendoscopic approaches in anterior skull base surgery
Evan Joyce1, Michael Karsy1, Serge Makarenko1
1Department of Neurosurgery, Clinical Neurosciences Center, University of Utah; and.
Abstract:
Anterior skull base approaches have included endoscopic or open microsurgical approaches for intracranial pathologies. However, discussion of a combined hybrid, cranioendoscopic approach, leveraging the benefits of both techniques, has been limited. Here we describe a case of a combined endoscopic, endonasal, and open microsurgical frontotemporal approach for resection of a complex anterior skull base lesion. A 62-year-old man with a large meningioma extending intradurally through the cribiform plate and sphenoethmoidal sinuses underwent a cranioendoscopic resection. Surgical techniques, including repair of the anterior skull base defect as well as complication avoidance and the coordination of multiple surgeons, are discussed. The video can be found here: https://youtu.be/Ti9tUUdWgJc.

