Related Experiment Video
Updated: Aug 24, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Endoscopic endonasal approach for resection of pediatric chordoma with brainstem invasion
Kumar Abhinav1, David Hong1, Carol H Yan2
1Departments of Neurosurgery and.
Insights
This study details a minimally invasive endoscopic endonasal approach for resecting a recurrent pontine chordoma in a pediatric patient. The technique allowed for complete tumor removal while preserving critical neurovascular structures.
Area of Science:
- Neurosurgery
- Endoscopic Skull Base Surgery
- Pediatric Oncology
Background:
- Chordomas are rare bone tumors that can occur along the skull base.
- Recurrence necessitates advanced surgical techniques for complete resection.
- Minimally invasive approaches are increasingly favored for complex skull base tumors.
Purpose of the Study:
- To describe the surgical technique and outcomes of an endoscopic endonasal approach for a recurrent pontine chordoma.
- To evaluate the feasibility and safety of this approach in a pediatric patient.
Main Methods:
- Orbitozygomatic craniotomy followed by endoscopic endonasal approach for tumor resection.
- Extensive clival and posterior clinoid exposure with internal carotid artery skeletonization.
- Resection of tumor from dural layers and brainstem, preserving neurovascular structures.
Main Results:
- Complete resection of the chordoma was achieved.
- The patient remained neurologically intact postoperatively.
- The endoscopic endonasal approach facilitated safe tumor removal from critical anatomical locations.
Conclusions:
- The endoscopic endonasal approach is a viable and effective option for managing recurrent pontine chordomas.
- This minimally invasive technique allows for maximal tumor resection with minimal morbidity.
- Preservation of the abducens nerve and pontine perforators is achievable with meticulous surgical technique.
Abstract:
A 14-year-old boy had undergone an orbitozygomatic craniotomy for a pontine lesion. There was growth on surveillance imaging with involvement of posterior clinoids, clivus, and left pons suggestive of chordoma (Fernandez-Miranda et al., 2014b). An endoscopic endonasal approach was undertaken involving full upper and midclival exposure including bilateral posterior clinoidectomy (Fernandez-Miranda et al., 2014a; Truong et al., 2019a, 2019b). The internal carotid artery was skeletonized to maximize exposure and facilitate safe resection. The tumor was removed from between the dural layers of the midclivus while preserving the interdural abducens nerve (Barges-Coll et al., 2010). The brainstem component was resected while preserving the pontine perforators. Postoperative diagnosis was chordoma with MRI demonstrating complete resection. The patient was intact postoperatively. The video can be found here: https://youtu.be/g6SQ5JVK0Ko.

