Related Experiment Video

Updated: Aug 24, 2025

Semi-automated Optical Heartbeat Analysis of Small Hearts
12:10

Semi-automated Optical Heartbeat Analysis of Small Hearts

Published on: September 16, 2009

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[The "Mickey Mouse Heart"]

Judith Meyer1, Laurent M Haegeli1, Miriam Brinkert1

  • 1Kardiologie, Kantonsspital Aarau, Aarau, Schweiz.

Praxis
|October 26, 2022
PubMed

Insights

The "Mickey Mouse Heart" syndrome affects elderly patients with heart failure with preserved ejection fraction (HFpEF), characterized by enlarged atria and heart valves. Underlying causes remain unknown, but standard therapies are recommended.

Area of Science:

  • Cardiology
  • Heart Failure Research

Context:

  • The
  • Mickey Mouse Heart
  • syndrome is a complex cardiac condition observed in patients, frequently elderly, with heart failure with preserved ejection fraction (HFpEF).
  • It is characterized by significant biatrial dilatation and enlargement of the mitral and tricuspid annuli.

Purpose:

  • To describe the clinical presentation and associated features of the
  • Mickey Mouse Heart
  • syndrome.
  • To highlight the common co-occurrence of atrial fibrillation and severe mitral and tricuspid regurgitation in affected individuals.
  • To identify knowledge gaps regarding the underlying molecular mechanisms and risk factors for biatrial dilatation.

Summary:

  • The
  • Mickey Mouse Heart
  • syndrome encompasses HFpEF, massive biatrial dilatation, annular dilatation, atrial fibrillation, and severe mitral/tricuspid regurgitation.
  • Elderly patients are most commonly affected by this condition.
  • The etiology of the characteristic biatrial dilatation is currently unknown.

Impact:

  • Recommends guideline-directed medical therapy for heart failure.
  • Emphasizes the importance of evaluating early rhythm control strategies for atrial fibrillation.
  • Suggests prompt treatment for mitral and tricuspid regurgitation to manage symptoms and improve outcomes.

Keywords:
HFpEFMitralklappeninsuffizienzTrikuspidalklappeninsuffizienzVorhofflimmernatrial fibrillationbiatrial dilatationbiatriale Dilatationmitral regurgitationtricuspid regurgitation

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