Related Experiment Video
Updated: Aug 24, 2025
12:10
Semi-automated Optical Heartbeat Analysis of Small Hearts
Published on: September 16, 2009
12.3K
[The "Mickey Mouse Heart"]
Judith Meyer1, Laurent M Haegeli1, Miriam Brinkert1
1Kardiologie, Kantonsspital Aarau, Aarau, Schweiz.
Praxis
|October 26, 2022
Summary
The "Mickey Mouse Heart" syndrome affects elderly patients with heart failure with preserved ejection fraction (HFpEF), characterized by enlarged atria and heart valves. Underlying causes remain unknown, but standard therapies are recommended.
Area of Science:
- Cardiology
- Heart Failure Research
Context:
- The
- Mickey Mouse Heart
- syndrome is a complex cardiac condition observed in patients, frequently elderly, with heart failure with preserved ejection fraction (HFpEF).
- It is characterized by significant biatrial dilatation and enlargement of the mitral and tricuspid annuli.
Purpose:
- To describe the clinical presentation and associated features of the
- Mickey Mouse Heart
- syndrome.
- To highlight the common co-occurrence of atrial fibrillation and severe mitral and tricuspid regurgitation in affected individuals.
- To identify knowledge gaps regarding the underlying molecular mechanisms and risk factors for biatrial dilatation.
Summary:
- The
- Mickey Mouse Heart
- syndrome encompasses HFpEF, massive biatrial dilatation, annular dilatation, atrial fibrillation, and severe mitral/tricuspid regurgitation.
- Elderly patients are most commonly affected by this condition.
- The etiology of the characteristic biatrial dilatation is currently unknown.
Impact:
- Recommends guideline-directed medical therapy for heart failure.
- Emphasizes the importance of evaluating early rhythm control strategies for atrial fibrillation.
- Suggests prompt treatment for mitral and tricuspid regurgitation to manage symptoms and improve outcomes.
Keywords:
HFpEFMitralklappeninsuffizienzTrikuspidalklappeninsuffizienzVorhofflimmernatrial fibrillationbiatrial dilatationbiatriale Dilatationmitral regurgitationtricuspid regurgitationMore Related Videos
Related Concept Videos
01:16Chambers of the Heart
5.6K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
5.6K
01:27Anatomy of the Heart
110.1K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
110.1K
01:15Heart Sounds
2.2K
Heart sounds are generated by the turbulence in blood flow due to the closing of heart valves. These sounds are best perceived slightly away from the valves, where the blood flow disseminates the sound.
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
2.2K
01:07Overview of the Heart
6.8K
The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's structure...
The heart's structure...
6.8K
01:15Layers of the Heart Wall
3.0K
The heart wall comprises three distinct layers: the epicardium, myocardium, and endocardium. The outermost layer, the epicardium, is the visceral layer of the serous pericardium, featuring a thin, transparent mesothelial surface and an inner layer of areolar connective tissue with fat deposits that increase with age.
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
3.0K
01:27Development of the Heart
1.1K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
1.1K