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Related Concept Videos

Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
579
Tooth Anatomy01:21

Tooth Anatomy

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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Oral Cavity01:11

Oral Cavity

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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
1.1K
Biofilms01:29

Biofilms

195
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
195
Assessment of the Mouth01:26

Assessment of the Mouth

342
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
342

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Related Experiment Video

Updated: Aug 24, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

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Oral Microbiome and Dental Caries Development.

Josie Shizhen Zhang1, Chun-Hung Chu1, Ollie Yiru Yu1

  • 1Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.

Dentistry Journal
|October 26, 2022
PubMed
Summary

Dental caries, a common oral disease, is linked to oral bacteria. Advanced sequencing and multi-omics approaches offer deeper insights into the oral microbiome

Keywords:
cariogenic bacteriadental cariesoral microbiologyoral microbiomeprecision dentistry

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Area of Science:

  • Oral microbiology
  • Dental caries research
  • Microbiome analysis

Background:

  • Dental caries is the most common oral disease globally, strongly associated with oral cavity microbiota.
  • Traditional methods for studying dental caries microbiology have limitations in identifying all oral microorganisms.
  • Recent advancements in sequencing and bioinformatics have significantly enhanced understanding of the oral microbiome.

Purpose of the Study:

  • To provide an overview of oral microbiome research in relation to dental caries development.
  • To review classical concepts and update knowledge on caries microbiology.
  • To discuss the etiological theory, key microorganisms, and microbiome shifts in dental caries.

Main Methods:

  • Review of classical culture-based and molecular methods.
  • Integration of sequencing-based technologies and bioinformatics analysis.
  • Application of multi-omics techniques including metagenomics, transcriptomics, and metabolomics.

Main Results:

  • Sequencing technologies have expanded the understanding of the oral microbiome beyond culturable organisms.
  • Microbial composition alone is insufficient to fully explain the link between the microbiome and caries.
  • Multi-omics approaches provide a comprehensive view of microbial contributions to dental caries.

Conclusions:

  • The study highlights the evolution of dental caries research from traditional methods to advanced multi-omics strategies.
  • Understanding the dynamic shifts and functional roles within the oral microbiome is crucial for unraveling caries etiology.
  • Comprehensive analysis of the oral microbiome offers new perspectives on dental caries development and prevention.