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Cannabidiol in Dentistry: A Scoping Review.
Carla David1,2, Alejandro Elizalde-Hernández2, Andressa S Barboza2
1Biopathological Research Group, Faculty of Dentistry (GIBFO), University of the Andes Mérida, Mérida 5101, Venezuela.
Dentistry Journal
|October 26, 2022
Summary
Cannabidiol (CBD) shows promise for dental applications, particularly in periodontal therapy and bone regeneration. Current research focuses on animal and cellular studies, with significant patent activity in oral care compositions.
Area of Science:
- Oral Health and Pharmacology
- Biomaterials Science
Background:
- Cannabidiol (CBD) is increasingly recognized but underexplored in dental research.
- Existing studies are primarily preclinical, lacking human clinical trials.
Purpose of the Study:
- To map the scientific and technological landscape of CBD in dentistry.
- To identify current and potential applications of CBD in oral health.
Main Methods:
- Scoping review of peer-reviewed articles from five databases.
- Search of patents from five technological platforms.
- Inclusion of 11 articles and 13 patents related to CBD in dentistry.
Main Results:
- No clinical studies found; research focused on animal (63.6%) and cellular (36.4%) models.
- Key applications identified: periodontal therapy (45.4%), bone regeneration (27.3%), and general oral therapies (27.3%).
- Patents predominantly claim oral care compositions, including tooth whitening, injury repair, and anti-inflammatory/analgesic effects, with significant industry involvement.
Conclusions:
- CBD exhibits promising biological properties for diverse dental applications.
- Industrial interest centers on oral care compositions, indicating a gap for further research and development.
- Substantial opportunities exist for advancing CBD research and technology in dentistry.
