Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Removing Lipid Droplets Improves Fat Transplantation Outcomes in a Mouse Model through Suppressing Pro-fibrotic Macrophage Responses.

Aesthetic plastic surgery·2026
Same author

Synergistic integration of ADSCs and egg white hydrogel microspheres for accelerated wound regeneration.

Journal of materials chemistry. B·2025
Same author

Immunomodulation in diabetic wounds healing: The intersection of macrophage reprogramming and immunotherapeutic hydrogels.

Journal of tissue engineering·2024
Same author

Microenvironmental dynamics of diabetic wounds and insights for hydrogel-based therapeutics.

Journal of tissue engineering·2024
Same author

Lipolysis inhibition improves the survival of fat grafts through ameliorating lipotoxicity and inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2024
Same author

Facile synthesis of hydroxypropyl chitosan-egg white hydrogel dressing with antibacterial and antioxidative activities for accelerating the healing of burn wounds.

Journal of materials chemistry. B·2023

Related Experiment Video

Updated: Aug 24, 2025

Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.2K

Recent Advances in Macroporous Hydrogels for Cell Behavior and Tissue Engineering.

Yuan Ma1, Xinhui Wang1, Ting Su1

  • 1Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou 510515, China.

Gels (Basel, Switzerland)
|October 26, 2022
PubMed
Summary
This summary is machine-generated.

Macroporous hydrogels overcome limitations of traditional hydrogels, enhancing cell survival and tissue regeneration. This review explores their advantages, preparation methods, and future potential in tissue engineering.

Keywords:
biochemical cuescell behaviorsmacroporous hydrogelsmatrix mechanicstissue engineering

More Related Videos

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

6.8K
Author Spotlight: A Novel Approach for Embedding Cell-Free Protein Synthesis Reactions in Hydrogels
06:38

Author Spotlight: A Novel Approach for Embedding Cell-Free Protein Synthesis Reactions in Hydrogels

Published on: June 23, 2023

1.3K

Related Experiment Videos

Last Updated: Aug 24, 2025

Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.2K
Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

6.8K
Author Spotlight: A Novel Approach for Embedding Cell-Free Protein Synthesis Reactions in Hydrogels
06:38

Author Spotlight: A Novel Approach for Embedding Cell-Free Protein Synthesis Reactions in Hydrogels

Published on: June 23, 2023

1.3K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Hydrogels are widely used in tissue engineering due to their biocompatibility and similarity to the extracellular matrix.
  • Submicron/nanosized pores in conventional hydrogels hinder cell survival and tissue regeneration.
  • Macroporous hydrogels offer improved nutrient transport, waste removal, and space for cellular activities.

Purpose of the Study:

  • To review the advantages and challenges of macroporous hydrogels in regulating cellular behavior.
  • To discuss advanced methods for preparing macroporous hydrogels to modulate cell behavior.
  • To explore future research directions in macroporous hydrogels for tissue engineering.

Main Methods:

  • Literature review of existing research on macroporous hydrogels.
  • Analysis of strategies for creating and functionalizing macroporous hydrogel scaffolds.
  • Discussion of methods to modulate cellular behavior using macroporous hydrogels.

Main Results:

  • Macroporous hydrogels significantly enhance cell adhesion, proliferation, migration, and differentiation compared to conventional hydrogels.
  • Various fabrication techniques enable control over pore size and structure for optimized cell infiltration and tissue formation.
  • Macroporosity facilitates nutrient and oxygen supply, crucial for cell viability and engineered tissue development.

Conclusions:

  • Macroporous hydrogels represent a significant advancement over traditional hydrogels for tissue engineering applications.
  • Tailored fabrication methods are key to optimizing macroporous hydrogel properties for specific regenerative medicine needs.
  • Further research into functionalization and in vivo applications will unlock the full potential of macroporous hydrogels.