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Updated: Aug 24, 2025

Determination of Total Lipid and Lipid Classes in Marine Samples
Published on: December 11, 2021
The Tetrahydrofuran Motif in Marine Lipids and Terpenes
Paula González-Andrés1, Laura Fernández-Peña1, Carlos Díez-Poza2
1Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Abstract:
Heterocycles are particularly common moieties within marine natural products. Specifically, tetrahydrofuranyl rings are present in a variety of compounds which present complex structures and interesting biological activities. Focusing on terpenoids, a high number of tetrahydrofuran-containing metabolites have been isolated during the last decades. They show promising biological activities, making them potential leads for novel antibiotics, antikinetoplastid drugs, amoebicidal substances, or anticancer drugs. Thus, they have attracted the attention of the synthetics community and numerous approaches to their total syntheses have appeared. Here, we offer the reader an overview of marine-derived terpenoids and related compounds, their isolation, structure determination, and a special focus on their total syntheses and biological profiles.
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