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Updated: Aug 24, 2025

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
[Cardiovascular magnetic resonance in myocardial infarction with non-obstructive coronary arteries]
E S Pershina1, D Y Shchekochikhin1,2,3, G M Shaginyan1
1Pirogov First City Clinical Hospital.
Insights
Cardiovascular magnetic resonance (CMR) effectively diagnoses myocardial infarction with nonobstructed coronary arteries (MINOCA), differentiating between ischemic and non-ischemic causes when clinical data is insufficient.
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Performance
Context:
- Myocardial infarction with nonobstructed coronary arteries (MINOCA) presents a diagnostic challenge.
- Distinguishing between ischemic and non-ischemic etiologies of MINOCA is crucial for appropriate patient management.
- Cardiovascular magnetic resonance (CMR) is increasingly utilized for cardiac assessment.
Purpose:
- To evaluate the diagnostic performance of cardiovascular magnetic resonance (CMR) in patients presenting with myocardial infarction with nonobstructed coronary arteries (MINOCA).
- To assess CMR's ability to differentiate between ischemic and non-ischemic causes of MINOCA.
Summary:
- A study included 46 patients with MINOCA who underwent CMR (T2-weighted imaging, cine-CMR, late gadolinium enhancement [LGE]).
- CMR identified myocardial infarction (MI) patterns in 30.4%, myocarditis in 26.1%, and hypertrophic cardiomyopathy in 13.1%.
- CMR established the precise clinical diagnosis in 73.9% of cases, proving superior to clinical data alone for differentiating MINOCA causes.
Impact:
- CMR provides a high diagnostic yield in MINOCA, guiding treatment decisions.
- This study highlights CMR's critical role in diagnosing diverse cardiac conditions presenting as MINOCA.
- Accurate diagnosis via CMR improves patient outcomes by enabling targeted therapies.
Aim:
To analyze diagnostic performance of cardiovascular magnetic resonance (CMR) in patients, presented with myocardial infarction with nonobstructed coronary arteries (MINOCA). Materials ant methods. 46 consecutives patients presented with myocardial infarction without evidence of obstructive coronary disease on angiography between January, 1 2018 and October 1, 2019 were included in the study. All patients underwent CMR within 10 days after admission. MRI was performed on 1.5 T Magnetic Resonance Imaging (MRI) using comprehensive protocol (T2-images, Cine-CMR, late gadolinium enhancement (LGE)).
Results:
CMR revealed myocardial infarction (MI) pattern in 14 patients (30.4%), myocarditis in 12 (26.1%), hypertrophic cardiomyopathy in 6 (13.1%). In 14 patients (30.4%) no LGE was observed. Notably in 2 patients without LGE features of takotsubo syndrome were noted. Mean age was significantly lower in patients with MI versus patient with non-ischemic causes of MINOCA (56.112.3 vs 64.612.8; p=0.04). ST elevation at admission frequency didnt differ between MI and non-ischemic patients (35.7% vs 25.0%; p=0.76). However MI patients had significantly increased troponin level, 0.87 [0.22; 1.85] vs 0.22 [0.07; 0.38]; p=0.008. CMR allowed to establish the prcised clinical diagnosis in 73.9% of the cases.
Conclusion:
Clinical data doesnt allow to differentiate ischemic or non-ischemic causes of MINOCA. However, CMR establish the correct diagnosis in most cases.
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