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[Classification of systemic vasculitis: evolution from eponyms to modern criteria]
N M Bulanov1, P I Novikov1, M A Litvinova1
1Sechenov First Moscow State Medical University (Sechenov University).
Terapevticheskii Arkhiv
|October 26, 2022
Summary
Systemic vasculitis classification has evolved from early descriptions to international standards. Recent advancements, including new criteria for specific conditions, reflect a deeper understanding of autoimmune vascular inflammation.
Area of Science:
- Rheumatology and Immunology
- Autoimmune Diseases
- Vascular Medicine
Context:
- Systemic vasculitis encompasses autoimmune diseases causing blood vessel inflammation.
- Historical classification efforts date back to the mid-20th century.
- International nomenclature established in 1994, revised in 2012, guides current understanding.
Purpose:
- To trace the historical evolution of systemic vasculitis classification.
- To highlight key milestones in developing diagnostic and classification criteria.
- To underscore the impact of etiological and pathogenetic research on classification.
Summary:
- Classification principles evolved from vessel size and etiology to international consensus.
- The American College of Rheumatology (ACR) and European Alliance of Associations for Rheumatology (EULAR) collaborated on new criteria.
- New criteria for granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis were published in 2022.
Impact:
- Facilitated large-scale research through standardized criteria.
- Improved diagnostic accuracy and clinical trial design.
- Reflects progress in understanding complex autoimmune vascular diseases.
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