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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
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Published on: January 30, 2017

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Influenza and other respiratory viruses in children: prevalence and clinical features

Paulo Alex N Silva1, Célia Regina Malveste Ito1, André Luís Elias Moreira1

  • 1Microorganism Biotechnology Laboratory of Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|October 26, 2022
PubMed

Insights

Rhinoviruses were the most common respiratory virus in children, followed by adenoviruses, metapneumoviruses, and influenza. This study highlights key viral agents causing acute respiratory infections (ARI) in pediatric populations.

Area of Science:

  • Pediatrics
  • Virology
  • Epidemiology

Background:

  • The ongoing COVID-19 pandemic coincides with seasonal influenza and other respiratory virus epidemics.
  • Understanding the prevalence of various respiratory viruses is crucial for public health.
  • Pediatric populations are particularly vulnerable to acute respiratory infections (ARI).

Purpose of the Study:

  • To identify the most prevalent respiratory viruses in pediatric patients during a specific epidemic season.
  • To analyze the clinical manifestations and demographic data associated with these viral infections.
  • To inform prevention strategies for respiratory infections in children.

Main Methods:

  • Collection and testing of 606 patient specimens for respiratory viruses.
  • RNA extraction and real-time reverse transcription polymerase chain reaction (RT-PCR) for viral detection.
  • Analysis of viral prevalence, patient demographics, and clinical symptoms.

Main Results:

  • Rhinovirus was the most prevalent virus, detected in 186 (45.47%) specimens.
  • Influenza A, influenza A (H1N1), and influenza B were identified in patients aged 18 days to 13 years.
  • Clinical manifestations included cough and asthma, with a female prevalence for influenza.
  • Key identified agents of ARI in pediatrics were rhinoviruses, adenoviruses, metapneumoviruses, and influenza.

Conclusions:

  • Rhinoviruses are a significant cause of ARI in pediatric patients.
  • Adenoviruses, metapneumoviruses, and influenza also play important roles in pediatric respiratory illnesses.
  • Data from Goiânia's respiratory infection epidemic period can guide public health prevention strategies.

Keywords:
EpidemiologyICUInfluenza AInfluenza BRespiratory virusesSurveillance

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