Related Experiment Video
Updated: Aug 24, 2025
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
International trends in pulmonary neuroendocrine cancer studies:a scientometric study
Hugo Tanaka1, Auro Del Giglio1
1Centro Universitário FMABC, Santo André, SP, Brazil.
Introduction:
Pulmonary neuroendocrine tumors account for approximately 20% of all primary lung tumors. Few studies summarize the current body of pulmonary neuroendocrine tumors studies worldwide.
Objective:
A quantitative scientometric analysis was conducted to evaluate the development of applications and innovations and to analyze their contribution to various areas of improvement in treatment and diagnosis of pulmonary neuroendocrine tumors.
Methods:
We searched for studies published in the last 20 years in the databases United States National Library of Medicine (PubMed), Scientific Electronic Library Online (SciELO), Scopus, and Web of Science, using the terms 'pulmonary neuroendocrine tumors', 'bronchial neuroendocrine tumors', 'bronchial carcinoid tumors', 'pulmonary carcinoid', 'typical pulmonary carcinoid', 'atypical pulmonary carcinoid', 'pulmonary carcinoid and diagnosis', 'pulmonary carcinoid and treatment', 'pulmonary carcinoid and epidemiology' and 'pulmonary carcinoid and prognosis'.
Results:
Our results showed the number of publications increased significantly over the study period and was strongly associated with the economic or financial situation of the publications' countries of origin. We observed a predominance of studies on histological diagnosis compared to treatment, and among the studies related to treatment, a predominance of retrospective studies relative to prospective studies was found.
Conclusion:
Based on the published literature, we concluded research on pulmonary neuroendocrine tumors still seems to be incipient, because it favors studies related to histological characterization of the disease, and therapeutic studies are still predominantly of a retrospective nature.
Insights
Research on pulmonary neuroendocrine tumors (PNETs) is growing, but still focuses heavily on histological diagnosis. Therapeutic studies for PNETs are predominantly retrospective, indicating an early stage of research development.
Area of Science:
- Oncology
- Pulmonology
- Medical Research Evaluation
Background:
- Pulmonary neuroendocrine tumors (PNETs) constitute approximately 20% of all primary lung tumors.
- A limited number of studies globally summarize the existing research landscape of PNETs.
Purpose of the Study:
- To perform a quantitative scientometric analysis of PNET research.
- To evaluate the evolution of PNET applications and innovations.
- To assess the contribution of PNET research to treatment and diagnostic advancements.
Main Methods:
- Conducted a 20-year literature search across PubMed, SciELO, Scopus, and Web of Science.
- Utilized comprehensive search terms including 'pulmonary neuroendocrine tumors', 'bronchial carcinoid', and related diagnostic, treatment, epidemiological, and prognostic terms.
- Focused on publications from the last two decades to capture recent trends.
Main Results:
- A significant increase in PNET publications over the study period was observed.
- Publication volume correlated strongly with the economic status of the countries of origin.
- Histological diagnosis research predominated over treatment research, with retrospective studies being more common than prospective ones in the treatment domain.
Conclusions:
- PNET research remains in its early stages, emphasizing histological characterization.
- Therapeutic research for PNETs is predominantly retrospective, suggesting a need for more prospective clinical trials.
- Further research is needed to advance PNET treatment and diagnosis.
