Related Experiment Video
Updated: Aug 24, 2025

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
Published on: January 20, 2022
Canine mitral valve size as measured by computed tomography
Wanda J Gordon-Evans1, K Helena Montin1, Christopher P Ober2
1Veterinary Clinical Sciences Department, Veterinary Medical Center, University of Minnesota, St. Paul, MN.
Mitral annulus measurements in dogs using CT scans are reliable and consistent among observers. This research supports future treatments for mitral valve dysfunction and enlargement in canine patients.
Area of Science:
- Veterinary Cardiology
- Medical Imaging
- Canine Anatomy
Background:
- Mitral valve dysfunction is a common cardiac condition in dogs.
- Accurate measurement of the mitral annulus is crucial for assessing disease severity and guiding treatment.
- Computed tomography (CT) offers high-resolution imaging for cardiovascular assessment.
Purpose of the Study:
- To establish reliable methods for measuring the canine mitral annulus using CT.
- To assess the interobserver reliability of these measurements.
- To provide reference values for normal canine mitral annulus dimensions.
Main Methods:
- Thoracic CT scans from 233 dogs without heart disease were analyzed.
- Five investigators used multiplanar reformatting to measure mitral valve dimensions and T4 length.
- Interobserver reliability was assessed by having all investigators measure 10 randomly selected animals.
Main Results:
- Excellent interobserver agreement (intraclass correlations > 0.9) was achieved for all measurements.
- Reference ranges for trigone-to-trigone distance (17.2 ± 4.7 mm) and circumference (79.0 ± 17.5 mm) were established.
- Normalized circumference by T4 length was 5.7 ± 0.7 mm, providing a standardized metric.
Conclusions:
- CT-based measurements of the canine mitral annulus are reproducible and consistent.
- This study provides essential anatomical data for diagnosing and managing canine mitral valve disease.
- Findings can aid in developing targeted therapies for mitral valve dysfunction and annular enlargement.
More Related Videos
12:12Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
07:42An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Related Concept Videos
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...