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Iodine Intake and Related Cognitive Function Impairments in Elementary Schoolchildren
Helga B Bailote1, Diana Linhares2, Célia Carvalho3,4
1Faculty of Sciences and Technology, University of the Azores, 9501-801 Ponta Delgada, Portugal.
Biology
|October 27, 2022
Summary
Moderate iodine deficiency significantly impairs cognitive function in schoolchildren. Children with iodine deficiency showed a 15-point lower Full-Scale IQ, impacting educational performance.
Area of Science:
- Nutritional Neuroscience
- Child Development
Background:
- Iodine deficiency is a leading cause of preventable intellectual disability globally.
- Previous research suggests a link between iodine deficiency and reduced intellectual function.
- Limited studies have assessed cognitive function in iodine-deficient schoolchildren using comprehensive intelligence scales.
Purpose of the Study:
- To investigate the impact of moderate iodine deficiency on the cognitive function of schoolchildren aged 7-11.
- To compare cognitive abilities between moderately iodine-deficient children and those with adequate iodine intake.
Main Methods:
- Cross-sectional study involving 256 schoolchildren (3rd and 4th grades).
- Initial intelligence quotient (IQ) assessment using Raven's Colored Progressive Matrices (CPM).
- Detailed cognitive assessment using the Wechsler Intelligence Scale for Children (WISC-III) in selected iodine-deficient and adequate-intake subgroups.
Main Results:
- The moderately iodine-deficient subgroup (n=30) exhibited a Full-Scale IQ 15.13 points lower than the adequate iodine intake subgroup (n=30).
- A significant effect size (d = 0.7, p = 0.013) was observed, indicating a substantial impact.
- Significant differences were found in 6 out of 13 WISC-III subtests, affecting both Verbal and Performance IQ.
Conclusions:
- Moderate iodine deficiency substantially impairs cognitive development and functioning in schoolchildren.
- Iodine deficiency adversely affects both verbal and performance intelligence, negatively impacting educational outcomes.
- The WISC-III is a valuable tool for assessing cognitive deficits in iodine-deficient schoolchildren.
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