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Current and Perspective Sensing Methods for Monkeypox Virus.

Ijaz Gul1,2, Changyue Liu1,2, Xi Yuan1,2

  • 1Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.

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|October 27, 2022
PubMed
Summary
This summary is machine-generated.

The monkeypox virus (MPXV) outbreak requires rapid, accurate detection methods. This review evaluates current MPXV diagnostic techniques, offering solutions for better global health control.

Keywords:
LAMPRPAdiagnosisimmunoassaymonkeypoxreal-time PCR

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Area of Science:

  • Virology
  • Public Health
  • Diagnostic Technologies

Background:

  • The global emergence of monkeypox virus (MPXV) presents a significant public health and economic threat.
  • Lessons from the COVID-19 pandemic highlight the critical need for efficient virus detection in disease control.
  • A timely evaluation of MPXV detection methods is crucial for ongoing control and prevention efforts.

Purpose of the Study:

  • To critically evaluate existing MPXV detection methods.
  • To discuss the advantages and disadvantages of various diagnostic approaches.
  • To propose solutions for improving MPXV diagnosis and control.

Main Methods:

  • Review of traditional and emerging nucleic acid detection techniques.
  • Evaluation of immunodiagnostic methods for MPXV.
  • Assessment of whole-particle and imaging-based detection strategies.

Main Results:

  • Analysis of the strengths and weaknesses of current MPXV diagnostic tools.
  • Identification of areas for improvement in sensitivity, specificity, and cost-effectiveness.
  • Comparison of different detection modalities for MPXV.

Conclusions:

  • Effective MPXV control relies on the development and implementation of advanced diagnostic techniques.
  • Further research is needed to refine existing methods and explore novel approaches for MPXV detection.
  • This review provides insights to guide the development of improved MPXV diagnostic tools for global health security.