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Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
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New Horizons for MXenes in Biosensing Applications.
Decheng Lu1, Huijuan Zhao1,2, Xinying Zhang1
1Department of Materials Genome Institute, Shanghai University, Shanghai 200444, China.
Biosensors
|October 27, 2022
Summary
MXenes, advanced two-dimensional materials, show great promise for developing highly sensitive and accurate biosensors. This review explores their recent applications in electrochemical and optical bioanalysis, highlighting future research directions.
Area of Science:
- Materials Science
- Biotechnology
- Analytical Chemistry
Background:
- Biosensors have advanced significantly for detecting disease biomarkers in body fluids.
- MXenes, a class of 2D materials, offer unique properties making them suitable for biosensor development.
Purpose of the Study:
- To systematically review the recent applications of MXenes in biosensing.
- To discuss current challenges and future prospects of MXenes in bioanalytical methods.
Main Methods:
- Review of literature on MXene-based biosensors.
- Focus on electrochemical and optical detection methods.
- Analysis of MXenes' properties relevant to biosensing.
Main Results:
- MXenes demonstrate high sensitivity, accuracy, and low cost in biosensing applications.
- Successful integration of MXenes in various electrochemical and optical biosensor platforms.
- Identification of key properties like surface chemistry and conductivity contributing to performance.
Conclusions:
- MXenes are versatile materials for next-generation biosensors.
- Further research is needed to address current limitations and optimize MXene-based biosensing.
- Interdisciplinary research can accelerate MXene applications in diagnostics.

